Host gene constraints and genomic context impact the expression and evolution of human microRNAs

Recent miRNAs tend to emerge within coding genes. Here, by analysing miRNA expression data from six species and comparing genomes from 13 species, the authors report that host genes may provide stronger expression constraints to intragenic miRNAs in the long run.

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Bibliographic Details
Main Authors: Gustavo S. França, Maria D. Vibranovski, Pedro A. F. Galante
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/714ff1a3aa5b4560b77772ee7d229898
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