U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study

Background: Previous studies have analyzed the association of aspect ratio (AR) on the ruptured intracranial aneurysm (IA), but the findings are inconclusive and controversial. Therefore, the study aimed to derive a more detailed estimation of this association between AR and ruptured IA in Chinese I...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jia-He Yin, Shi-Xing Su, Xin Zhang, Yi-Ming Bi, Chuan-Zhi Duan, Wei-mei Huang, Xi-Long Wang
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	aspect ratio (AR) rupture of intracranial aneurysm association generalized additive model subgroup analysis Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/715021a111c24787b9345ec9a076e5cf
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:715021a111c24787b9345ec9a076e5cf
record_format	dspace
spelling	oai:doaj.org-article:715021a111c24787b9345ec9a076e5cf2021-11-05T23:36:31ZU-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study1664-229510.3389/fneur.2021.731129https://doaj.org/article/715021a111c24787b9345ec9a076e5cf2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fneur.2021.731129/fullhttps://doaj.org/toc/1664-2295Background: Previous studies have analyzed the association of aspect ratio (AR) on the ruptured intracranial aneurysm (IA), but the findings are inconclusive and controversial. Therefore, the study aimed to derive a more detailed estimation of this association between AR and ruptured IA in Chinese IA patients.Methods: The present work was a cross-sectional study. We retrospectively collected 1,588 Chinese patients with a single IA from January 2010 to November 2017. The relationship was examined between AR at diagnosis and ruptured IA. Covariates included data of demographics, morphological parameters, lifestyle habits, clinical features, and comorbidities. Binary logistic regression and two-piecewise linear models were used to analyze independent associations of AR with ruptured IA.Results: The results suggest that the association between AR and IA rupture was U-shaped. In the AR range of 1.08–1.99, the prevalence of IA rupture was 13% lower for each 0.1-unit increment in AR [odds ratio 0.87, 95% confidence interval (CI) 0.80–0.98]. Conversely, for every 0.1-unit increase in AR, the prevalence of IA rupture increased by ~3% (odds ratio 1.03, 95% CI 1.01–1.06) in the AR range of 3.42–4.08.Conclusion: The relationship between AR and ruptured IA was U-shaped, with the negative association at AR of 1.08–1.99 and positive association at AR of 3.42–4.08.Jia-He YinShi-Xing SuXin ZhangYi-Ming BiYi-Ming BiChuan-Zhi DuanWei-mei HuangXi-Long WangFrontiers Media S.A.articleaspect ratio (AR)rupture of intracranial aneurysmassociationgeneralized additive modelsubgroup analysisNeurology. Diseases of the nervous systemRC346-429ENFrontiers in Neurology, Vol 12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	aspect ratio (AR) rupture of intracranial aneurysm association generalized additive model subgroup analysis Neurology. Diseases of the nervous system RC346-429
spellingShingle	aspect ratio (AR) rupture of intracranial aneurysm association generalized additive model subgroup analysis Neurology. Diseases of the nervous system RC346-429 Jia-He Yin Shi-Xing Su Xin Zhang Yi-Ming Bi Yi-Ming Bi Chuan-Zhi Duan Wei-mei Huang Xi-Long Wang U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study
description	Background: Previous studies have analyzed the association of aspect ratio (AR) on the ruptured intracranial aneurysm (IA), but the findings are inconclusive and controversial. Therefore, the study aimed to derive a more detailed estimation of this association between AR and ruptured IA in Chinese IA patients.Methods: The present work was a cross-sectional study. We retrospectively collected 1,588 Chinese patients with a single IA from January 2010 to November 2017. The relationship was examined between AR at diagnosis and ruptured IA. Covariates included data of demographics, morphological parameters, lifestyle habits, clinical features, and comorbidities. Binary logistic regression and two-piecewise linear models were used to analyze independent associations of AR with ruptured IA.Results: The results suggest that the association between AR and IA rupture was U-shaped. In the AR range of 1.08–1.99, the prevalence of IA rupture was 13% lower for each 0.1-unit increment in AR [odds ratio 0.87, 95% confidence interval (CI) 0.80–0.98]. Conversely, for every 0.1-unit increase in AR, the prevalence of IA rupture increased by ~3% (odds ratio 1.03, 95% CI 1.01–1.06) in the AR range of 3.42–4.08.Conclusion: The relationship between AR and ruptured IA was U-shaped, with the negative association at AR of 1.08–1.99 and positive association at AR of 3.42–4.08.
format	article
author	Jia-He Yin Shi-Xing Su Xin Zhang Yi-Ming Bi Yi-Ming Bi Chuan-Zhi Duan Wei-mei Huang Xi-Long Wang
author_facet	Jia-He Yin Shi-Xing Su Xin Zhang Yi-Ming Bi Yi-Ming Bi Chuan-Zhi Duan Wei-mei Huang Xi-Long Wang
author_sort	Jia-He Yin
title	U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study
title_short	U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study
title_full	U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study
title_fullStr	U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study
title_full_unstemmed	U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study
title_sort	u-shaped association of aspect ratio and single intracranial aneurysm rupture in chinese patients: a cross-sectional study
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/715021a111c24787b9345ec9a076e5cf
work_keys_str_mv	AT jiaheyin ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT shixingsu ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT xinzhang ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT yimingbi ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT yimingbi ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT chuanzhiduan ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT weimeihuang ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy AT xilongwang ushapedassociationofaspectratioandsingleintracranialaneurysmruptureinchinesepatientsacrosssectionalstudy
_version_	1718443986870337536

U-Shaped Association of Aspect Ratio and Single Intracranial Aneurysm Rupture in Chinese Patients: A Cross-Sectional Study

Ejemplares similares