Comparison of anterior chamber flare among different glaucoma surgeries

Masaki Tanito,1,2 Kaoru Manabe,1 Mihoko Mochiji,1 Yasuyuki Takai,1 Yotaro Matsuoka21Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan; 2Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, JapanCorrespondence: Masaki TanitoDepartment of Ophthalmology, Shimane...

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Autores principales:	Tanito M, Manabe K, Mochiji M, Takai Y, Matsuoka Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Anterior chamber flare trabeculectomy EX-PRESS shunt microhook ab interno trabeculotomy minimally invasive glaucoma surgery (MIGS). Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/715656e7e524499cae976bcbee58b0bb
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spelling	oai:doaj.org-article:715656e7e524499cae976bcbee58b0bb2021-12-02T07:36:05ZComparison of anterior chamber flare among different glaucoma surgeries1177-5483https://doaj.org/article/715656e7e524499cae976bcbee58b0bb2019-08-01T00:00:00Zhttps://www.dovepress.com/comparison-of-anterior-chamber-flare-among-different-glaucoma-surgerie-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Masaki Tanito,1,2 Kaoru Manabe,1 Mihoko Mochiji,1 Yasuyuki Takai,1 Yotaro Matsuoka21Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan; 2Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, JapanCorrespondence: Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, JapanTel +81 85 320 2284Fax +81 85 320 2278Email tanito-oph@umin.ac.jpPurpose: To compare postsurgical anterior chamber flare (ACF) among conventional (trabeculectomy, LEC) and novel (EX-PRESS Shunt, EXP) filtration surgeries and microhook ab interno trabeculotomy (μLOT), a novel minimally invasive glaucoma surgery (MIGS).Subjects and methods: This retrospective study included 125 primary open angle glaucoma eyes (89 consecutive subjects) treated with μLOT (n=38), LEC (n=12), or EXP (n=75). The intraocular pressure (IOP), numbers of antiglaucoma medication, and ACF at preoperatively and 2 weeks; 1, 3, and 6 months postoperatively were compared among the surgical groups using a mixed-effects regression model.Results: The postoperative IOP (p<0.0001) and medication use were significantly (p<0.0001) lower in the LEC and EXP groups than with μLOT for up to 6 months postoperatively. The ACF differed significantly (p=0.0004) among groups; the ACF was significantly higher (p=0.0097, post-hoc Student’s t-test) with μLOT (33.6±52.8 pc/msec) than the EXP (15.7±19.9 pc/msec) at 2 weeks and was significantly (p=0.0111, post-hoc t-test) lower with μLOT (7.9±2.0 pc/msec) than LEC (12.0±6.1 pc/msec) at 6 months.Conclusion: Considering our observation, although its clinical significance is unclear, not all MIGS are minimally invasive regarding early postsurgical inflammation.Keywords: anterior chamber flare, trabeculectomy, EX-PRESS shunt, microhook ab interno trabeculotomy, minimally invasive glaucoma surgery, MIGSTanito MManabe KMochiji MTakai YMatsuoka YDove Medical PressarticleAnterior chamber flaretrabeculectomyEX-PRESS shuntmicrohook ab interno trabeculotomyminimally invasive glaucoma surgery (MIGS).OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 1609-1612 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Anterior chamber flare trabeculectomy EX-PRESS shunt microhook ab interno trabeculotomy minimally invasive glaucoma surgery (MIGS). Ophthalmology RE1-994
spellingShingle	Anterior chamber flare trabeculectomy EX-PRESS shunt microhook ab interno trabeculotomy minimally invasive glaucoma surgery (MIGS). Ophthalmology RE1-994 Tanito M Manabe K Mochiji M Takai Y Matsuoka Y Comparison of anterior chamber flare among different glaucoma surgeries
description	Masaki Tanito,1,2 Kaoru Manabe,1 Mihoko Mochiji,1 Yasuyuki Takai,1 Yotaro Matsuoka21Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan; 2Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, JapanCorrespondence: Masaki TanitoDepartment of Ophthalmology, Shimane University Faculty of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, JapanTel +81 85 320 2284Fax +81 85 320 2278Email tanito-oph@umin.ac.jpPurpose: To compare postsurgical anterior chamber flare (ACF) among conventional (trabeculectomy, LEC) and novel (EX-PRESS Shunt, EXP) filtration surgeries and microhook ab interno trabeculotomy (μLOT), a novel minimally invasive glaucoma surgery (MIGS).Subjects and methods: This retrospective study included 125 primary open angle glaucoma eyes (89 consecutive subjects) treated with μLOT (n=38), LEC (n=12), or EXP (n=75). The intraocular pressure (IOP), numbers of antiglaucoma medication, and ACF at preoperatively and 2 weeks; 1, 3, and 6 months postoperatively were compared among the surgical groups using a mixed-effects regression model.Results: The postoperative IOP (p<0.0001) and medication use were significantly (p<0.0001) lower in the LEC and EXP groups than with μLOT for up to 6 months postoperatively. The ACF differed significantly (p=0.0004) among groups; the ACF was significantly higher (p=0.0097, post-hoc Student’s t-test) with μLOT (33.6±52.8 pc/msec) than the EXP (15.7±19.9 pc/msec) at 2 weeks and was significantly (p=0.0111, post-hoc t-test) lower with μLOT (7.9±2.0 pc/msec) than LEC (12.0±6.1 pc/msec) at 6 months.Conclusion: Considering our observation, although its clinical significance is unclear, not all MIGS are minimally invasive regarding early postsurgical inflammation.Keywords: anterior chamber flare, trabeculectomy, EX-PRESS shunt, microhook ab interno trabeculotomy, minimally invasive glaucoma surgery, MIGS
format	article
author	Tanito M Manabe K Mochiji M Takai Y Matsuoka Y
author_facet	Tanito M Manabe K Mochiji M Takai Y Matsuoka Y
author_sort	Tanito M
title	Comparison of anterior chamber flare among different glaucoma surgeries
title_short	Comparison of anterior chamber flare among different glaucoma surgeries
title_full	Comparison of anterior chamber flare among different glaucoma surgeries
title_fullStr	Comparison of anterior chamber flare among different glaucoma surgeries
title_full_unstemmed	Comparison of anterior chamber flare among different glaucoma surgeries
title_sort	comparison of anterior chamber flare among different glaucoma surgeries
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/715656e7e524499cae976bcbee58b0bb
work_keys_str_mv	AT tanitom comparisonofanteriorchamberflareamongdifferentglaucomasurgeries AT manabek comparisonofanteriorchamberflareamongdifferentglaucomasurgeries AT mochijim comparisonofanteriorchamberflareamongdifferentglaucomasurgeries AT takaiy comparisonofanteriorchamberflareamongdifferentglaucomasurgeries AT matsuokay comparisonofanteriorchamberflareamongdifferentglaucomasurgeries
_version_	1718399343647522816

Comparison of anterior chamber flare among different glaucoma surgeries

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