Multiple myeloma: optimal management and long-term disease control

Priya Sriskandarajah, Faith E Davies Divisions of Molecular Pathology, Cancer Therapeutics, and Clinical Studies, Institute of Cancer Research, Sutton, UK Abstract: Multiple myeloma is an incurable hematological disease previously associated with poor prognosis and survival rates. However, followi...

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Autores principales:	Sriskandarajah P, Davies FE
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/715f124cb83c42f9956f29705311553d
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spelling	oai:doaj.org-article:715f124cb83c42f9956f29705311553d2021-12-02T07:01:49ZMultiple myeloma: optimal management and long-term disease control1179-9889https://doaj.org/article/715f124cb83c42f9956f29705311553d2014-11-01T00:00:00Zhttp://www.dovepress.com/multiple-myeloma-optimal-management-and-long-term-disease-control-peer-reviewed-article-BLCTThttps://doaj.org/toc/1179-9889 Priya Sriskandarajah, Faith E Davies Divisions of Molecular Pathology, Cancer Therapeutics, and Clinical Studies, Institute of Cancer Research, Sutton, UK Abstract: Multiple myeloma is an incurable hematological disease previously associated with poor prognosis and survival rates. However, following the advent of the so-called novel agents, the goal of therapy has now moved to long-term disease control and potential cure. However, despite these advances, myeloma displays considerable heterogeneity and, over time, control of disease can be lost. In order to counteract this, new strategies are incorporating risk stratification to provide more individualized therapy. Furthermore, there is now increasing focus on adapting therapy in elderly and frail patients to improve compliance and maximize treatment benefit. Keywords: combination regimes, frailty index, risk stratification, myelomaSriskandarajah PDavies FEDove Medical PressarticleDiseases of the blood and blood-forming organsRC633-647.5ENBlood and Lymphatic Cancer: Targets and Therapy, Vol 2014, Iss default, Pp 121-134 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Sriskandarajah P Davies FE Multiple myeloma: optimal management and long-term disease control
description	Priya Sriskandarajah, Faith E Davies Divisions of Molecular Pathology, Cancer Therapeutics, and Clinical Studies, Institute of Cancer Research, Sutton, UK Abstract: Multiple myeloma is an incurable hematological disease previously associated with poor prognosis and survival rates. However, following the advent of the so-called novel agents, the goal of therapy has now moved to long-term disease control and potential cure. However, despite these advances, myeloma displays considerable heterogeneity and, over time, control of disease can be lost. In order to counteract this, new strategies are incorporating risk stratification to provide more individualized therapy. Furthermore, there is now increasing focus on adapting therapy in elderly and frail patients to improve compliance and maximize treatment benefit. Keywords: combination regimes, frailty index, risk stratification, myeloma
format	article
author	Sriskandarajah P Davies FE
author_facet	Sriskandarajah P Davies FE
author_sort	Sriskandarajah P
title	Multiple myeloma: optimal management and long-term disease control
title_short	Multiple myeloma: optimal management and long-term disease control
title_full	Multiple myeloma: optimal management and long-term disease control
title_fullStr	Multiple myeloma: optimal management and long-term disease control
title_full_unstemmed	Multiple myeloma: optimal management and long-term disease control
title_sort	multiple myeloma: optimal management and long-term disease control
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/715f124cb83c42f9956f29705311553d
work_keys_str_mv	AT sriskandarajahp multiplemyelomaoptimalmanagementandlongtermdiseasecontrol AT daviesfe multiplemyelomaoptimalmanagementandlongtermdiseasecontrol
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Multiple myeloma: optimal management and long-term disease control

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