Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats

Diabetes mellitus (DM) and its complications impose a significant burden on patients and the health care system. In the Traditional Persian Medicine (TPM), barley is recommended for treatment of DM. This study sought to assess the effect of barley seed aqueous extract on hepatic, pancreatic, renal...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mohsen Naseri, Zahra Khalaj Sereshki, Behnaz Ghavami, Bagher Minaii Zangii, Mohammad Kamalinejad, Parvaneh Mohseni Moghaddam, Majid Asghari, Seyed Abbas Hashemi Nejad, Fatemeh Emadi, Farzaneh Ghaffari
Formato:	article
Lenguaje:	EN
Publicado:	PAGEPress Publications 2021
Materias:	Barley diabetes traditional persian medicine Streptozotocin diabetes mellitus Medicine R Human anatomy QM1-695
Acceso en línea:	https://doaj.org/article/71601bc178ca4d509c3c1f03d93dbcc3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:71601bc178ca4d509c3c1f03d93dbcc3
record_format	dspace
spelling	oai:doaj.org-article:71601bc178ca4d509c3c1f03d93dbcc32021-11-23T21:40:15ZPreliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats10.4081/ejtm.2022.101082037-74522037-7460https://doaj.org/article/71601bc178ca4d509c3c1f03d93dbcc32021-11-01T00:00:00Zhttps://www.pagepressjournals.org/index.php/bam/article/view/10108https://doaj.org/toc/2037-7452https://doaj.org/toc/2037-7460 Diabetes mellitus (DM) and its complications impose a significant burden on patients and the health care system. In the Traditional Persian Medicine (TPM), barley is recommended for treatment of DM. This study sought to assess the effect of barley seed aqueous extract on hepatic, pancreatic, renal and cardiac tissues in normal (non-diabetic) and Streptozotocin-induced diabetic rats. Twenty-one male Wistar rats were randomly divided into diabetic and non-diabetic groups. Diabetes was induced by single intraperitoneal injection of Streptozotocin. After one week, the diabetic and non-diabetic groups were randomly divided into control and barley seed extract subgroups namely N group (non-diabetic control rats), S group (seed extract treated non-diabetic rats), D group (diabetic control rats) and DS group (seed extract treated diabetic rats). After 6 weeks, all rats were sacrificed for histopathological analysis and specimens were stained routinely for histological studies. The abnormal histological signs significantly decreased in the DS group compared to D group. Also, protective effects of barley seed extract against histopathological changes were seen in S group compared to N group.These findings suggest that barley seed extract exerts a protective effect on different tissues in diabetes. Mohsen NaseriZahra Khalaj SereshkiBehnaz GhavamiBagher Minaii ZangiiMohammad KamalinejadParvaneh Mohseni MoghaddamMajid AsghariSeyed Abbas Hashemi NejadFatemeh EmadiFarzaneh GhaffariPAGEPress PublicationsarticleBarleydiabetestraditional persian medicineStreptozotocindiabetes mellitusMedicineRHuman anatomyQM1-695ENEuropean Journal of Translational Myology (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Barley diabetes traditional persian medicine Streptozotocin diabetes mellitus Medicine R Human anatomy QM1-695
spellingShingle	Barley diabetes traditional persian medicine Streptozotocin diabetes mellitus Medicine R Human anatomy QM1-695 Mohsen Naseri Zahra Khalaj Sereshki Behnaz Ghavami Bagher Minaii Zangii Mohammad Kamalinejad Parvaneh Mohseni Moghaddam Majid Asghari Seyed Abbas Hashemi Nejad Fatemeh Emadi Farzaneh Ghaffari Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
description	Diabetes mellitus (DM) and its complications impose a significant burden on patients and the health care system. In the Traditional Persian Medicine (TPM), barley is recommended for treatment of DM. This study sought to assess the effect of barley seed aqueous extract on hepatic, pancreatic, renal and cardiac tissues in normal (non-diabetic) and Streptozotocin-induced diabetic rats. Twenty-one male Wistar rats were randomly divided into diabetic and non-diabetic groups. Diabetes was induced by single intraperitoneal injection of Streptozotocin. After one week, the diabetic and non-diabetic groups were randomly divided into control and barley seed extract subgroups namely N group (non-diabetic control rats), S group (seed extract treated non-diabetic rats), D group (diabetic control rats) and DS group (seed extract treated diabetic rats). After 6 weeks, all rats were sacrificed for histopathological analysis and specimens were stained routinely for histological studies. The abnormal histological signs significantly decreased in the DS group compared to D group. Also, protective effects of barley seed extract against histopathological changes were seen in S group compared to N group.These findings suggest that barley seed extract exerts a protective effect on different tissues in diabetes.
format	article
author	Mohsen Naseri Zahra Khalaj Sereshki Behnaz Ghavami Bagher Minaii Zangii Mohammad Kamalinejad Parvaneh Mohseni Moghaddam Majid Asghari Seyed Abbas Hashemi Nejad Fatemeh Emadi Farzaneh Ghaffari
author_facet	Mohsen Naseri Zahra Khalaj Sereshki Behnaz Ghavami Bagher Minaii Zangii Mohammad Kamalinejad Parvaneh Mohseni Moghaddam Majid Asghari Seyed Abbas Hashemi Nejad Fatemeh Emadi Farzaneh Ghaffari
author_sort	Mohsen Naseri
title	Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
title_short	Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
title_full	Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
title_fullStr	Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
title_full_unstemmed	Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
title_sort	preliminary results of effect of barley (<em>hordeum vulgare l.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats
publisher	PAGEPress Publications
publishDate	2021
url	https://doaj.org/article/71601bc178ca4d509c3c1f03d93dbcc3
work_keys_str_mv	AT mohsennaseri preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT zahrakhalajsereshki preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT behnazghavami preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT bagherminaiizangii preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT mohammadkamalinejad preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT parvanehmohsenimoghaddam preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT majidasghari preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT seyedabbashasheminejad preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT fatemehemadi preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats AT farzanehghaffari preliminaryresultsofeffectofbarleyemhordeumvulgarelemextractonliverpancreaskidneysandcardiactissuesinstreptozotocininduceddiabeticrats
_version_	1718416098045460480

Preliminary results of effect of barley (<em>Hordeum vulgare L.</em>) extract on liver, pancreas, kidneys and cardiac tissues in streptozotocin induced diabetic rats

Ejemplares similares