Two forms of death in ageing Caenorhabditis elegans

Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are differentially affected by age and mutations tha...

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Autores principales: Yuan Zhao, Ann F. Gilliat, Matthias Ziehm, Mark Turmaine, Hongyuan Wang, Marina Ezcurra, Chenhao Yang, George Phillips, David McBay, William B. Zhang, Linda Partridge, Zachary Pincus, David Gems
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/71789ec218844f8ab9c0ea0c9fa9e546
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spelling oai:doaj.org-article:71789ec218844f8ab9c0ea0c9fa9e5462021-12-02T15:38:51ZTwo forms of death in ageing Caenorhabditis elegans10.1038/ncomms154582041-1723https://doaj.org/article/71789ec218844f8ab9c0ea0c9fa9e5462017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15458https://doaj.org/toc/2041-1723Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are differentially affected by age and mutations that extend worm lifespan.Yuan ZhaoAnn F. GilliatMatthias ZiehmMark TurmaineHongyuan WangMarina EzcurraChenhao YangGeorge PhillipsDavid McBayWilliam B. ZhangLinda PartridgeZachary PincusDavid GemsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuan Zhao
Ann F. Gilliat
Matthias Ziehm
Mark Turmaine
Hongyuan Wang
Marina Ezcurra
Chenhao Yang
George Phillips
David McBay
William B. Zhang
Linda Partridge
Zachary Pincus
David Gems
Two forms of death in ageing Caenorhabditis elegans
description Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are differentially affected by age and mutations that extend worm lifespan.
format article
author Yuan Zhao
Ann F. Gilliat
Matthias Ziehm
Mark Turmaine
Hongyuan Wang
Marina Ezcurra
Chenhao Yang
George Phillips
David McBay
William B. Zhang
Linda Partridge
Zachary Pincus
David Gems
author_facet Yuan Zhao
Ann F. Gilliat
Matthias Ziehm
Mark Turmaine
Hongyuan Wang
Marina Ezcurra
Chenhao Yang
George Phillips
David McBay
William B. Zhang
Linda Partridge
Zachary Pincus
David Gems
author_sort Yuan Zhao
title Two forms of death in ageing Caenorhabditis elegans
title_short Two forms of death in ageing Caenorhabditis elegans
title_full Two forms of death in ageing Caenorhabditis elegans
title_fullStr Two forms of death in ageing Caenorhabditis elegans
title_full_unstemmed Two forms of death in ageing Caenorhabditis elegans
title_sort two forms of death in ageing caenorhabditis elegans
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/71789ec218844f8ab9c0ea0c9fa9e546
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