Two forms of death in ageing Caenorhabditis elegans
Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are differentially affected by age and mutations tha...
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Nature Portfolio
2017
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oai:doaj.org-article:71789ec218844f8ab9c0ea0c9fa9e5462021-12-02T15:38:51ZTwo forms of death in ageing Caenorhabditis elegans10.1038/ncomms154582041-1723https://doaj.org/article/71789ec218844f8ab9c0ea0c9fa9e5462017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15458https://doaj.org/toc/2041-1723Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are differentially affected by age and mutations that extend worm lifespan.Yuan ZhaoAnn F. GilliatMatthias ZiehmMark TurmaineHongyuan WangMarina EzcurraChenhao YangGeorge PhillipsDavid McBayWilliam B. ZhangLinda PartridgeZachary PincusDavid GemsNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q Yuan Zhao Ann F. Gilliat Matthias Ziehm Mark Turmaine Hongyuan Wang Marina Ezcurra Chenhao Yang George Phillips David McBay William B. Zhang Linda Partridge Zachary Pincus David Gems Two forms of death in ageing Caenorhabditis elegans |
description |
Despite its wide use in ageing research, the contribution of specific age-associated pathologies toC. elegansmortality is not well understood. Here the authors identify two types of death in worms, with either a swollen or a shrunken pharynx, that are differentially affected by age and mutations that extend worm lifespan. |
format |
article |
author |
Yuan Zhao Ann F. Gilliat Matthias Ziehm Mark Turmaine Hongyuan Wang Marina Ezcurra Chenhao Yang George Phillips David McBay William B. Zhang Linda Partridge Zachary Pincus David Gems |
author_facet |
Yuan Zhao Ann F. Gilliat Matthias Ziehm Mark Turmaine Hongyuan Wang Marina Ezcurra Chenhao Yang George Phillips David McBay William B. Zhang Linda Partridge Zachary Pincus David Gems |
author_sort |
Yuan Zhao |
title |
Two forms of death in ageing Caenorhabditis elegans |
title_short |
Two forms of death in ageing Caenorhabditis elegans |
title_full |
Two forms of death in ageing Caenorhabditis elegans |
title_fullStr |
Two forms of death in ageing Caenorhabditis elegans |
title_full_unstemmed |
Two forms of death in ageing Caenorhabditis elegans |
title_sort |
two forms of death in ageing caenorhabditis elegans |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/71789ec218844f8ab9c0ea0c9fa9e546 |
work_keys_str_mv |
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