Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activation.
Efficient adaptive immune responses require the localization of T lymphocytes in secondary lymphoid organs and inflamed tissues. To achieve correct localization of T lymphocytes, the migration of these cells is initiated and directed by adhesion molecules and chemokines. It has recently been shown t...
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Autores principales: | Karin Knieke, Holger Lingel, Kathrin Chamaon, Monika C Brunner-Weinzierl |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/71811d8c62334cf594364583a295a14b |
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