Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases

Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 2...

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Autores principales:	Niti Sharma, Mario A. Tan, Seong Soo A. An
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	phytosterols neurodegeneration Alzheimer’s disease natural products blood brain barrier Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/71812166368a48edaf4f73859fe840a6
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spelling	oai:doaj.org-article:71812166368a48edaf4f73859fe840a62021-11-25T17:54:52ZPhytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases10.3390/ijms2222122551422-00671661-6596https://doaj.org/article/71812166368a48edaf4f73859fe840a62021-11-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/22/12255https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities.Niti SharmaMario A. TanSeong Soo A. AnMDPI AGarticlephytosterolsneurodegenerationAlzheimer’s diseasenatural productsblood brain barrierBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 12255, p 12255 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	phytosterols neurodegeneration Alzheimer’s disease natural products blood brain barrier Biology (General) QH301-705.5 Chemistry QD1-999
spellingShingle	phytosterols neurodegeneration Alzheimer’s disease natural products blood brain barrier Biology (General) QH301-705.5 Chemistry QD1-999 Niti Sharma Mario A. Tan Seong Soo A. An Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
description	Phytosterols constitute a class of natural products that are an important component of diet and have vast applications in foods, cosmetics, and herbal medicines. With many and diverse isolated structures in nature, they exhibit a broad range of biological and pharmacological activities. Among over 200 types of phytosterols, stigmasterol and β-sitosterol were ubiquitous in many plant species, exhibiting important aspects of activities related to neurodegenerative diseases. Hence, this mini-review presented an overview of the reported studies on selected phytosterols related to neurodegenerative diseases. It covered the major phytosterols based on biosynthetic considerations, including other phytosterols with significant in vitro and in vivo biological activities.
format	article
author	Niti Sharma Mario A. Tan Seong Soo A. An
author_facet	Niti Sharma Mario A. Tan Seong Soo A. An
author_sort	Niti Sharma
title	Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_short	Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_full	Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_fullStr	Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_full_unstemmed	Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases
title_sort	phytosterols: potential metabolic modulators in neurodegenerative diseases
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/71812166368a48edaf4f73859fe840a6
work_keys_str_mv	AT nitisharma phytosterolspotentialmetabolicmodulatorsinneurodegenerativediseases AT marioatan phytosterolspotentialmetabolicmodulatorsinneurodegenerativediseases AT seongsooaan phytosterolspotentialmetabolicmodulatorsinneurodegenerativediseases
_version_	1718411868412837888

Phytosterols: Potential Metabolic Modulators in Neurodegenerative Diseases

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