Regulation of lipid saturation without sensing membrane fluidity

Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. Here authors reconstituted the core machinery for regulating lipid saturation in baker’s yeast to directly characterize its response to defined memb...

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Autores principales:	Stephanie Ballweg, Erdinc Sezgin, Milka Doktorova, Roberto Covino, John Reinhard, Dorith Wunnicke, Inga Hänelt, Ilya Levental, Gerhard Hummer, Robert Ernst
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7183c9c33c7245fcb2bcf9a185481273
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spelling	oai:doaj.org-article:7183c9c33c7245fcb2bcf9a1854812732021-12-02T17:31:08ZRegulation of lipid saturation without sensing membrane fluidity10.1038/s41467-020-14528-12041-1723https://doaj.org/article/7183c9c33c7245fcb2bcf9a1854812732020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14528-1https://doaj.org/toc/2041-1723Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. Here authors reconstituted the core machinery for regulating lipid saturation in baker’s yeast to directly characterize its response to defined membrane environments and uncover its mode-of-action.Stephanie BallwegErdinc SezginMilka DoktorovaRoberto CovinoJohn ReinhardDorith WunnickeInga HäneltIlya LeventalGerhard HummerRobert ErnstNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephanie Ballweg Erdinc Sezgin Milka Doktorova Roberto Covino John Reinhard Dorith Wunnicke Inga Hänelt Ilya Levental Gerhard Hummer Robert Ernst Regulation of lipid saturation without sensing membrane fluidity
description	Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. Here authors reconstituted the core machinery for regulating lipid saturation in baker’s yeast to directly characterize its response to defined membrane environments and uncover its mode-of-action.
format	article
author	Stephanie Ballweg Erdinc Sezgin Milka Doktorova Roberto Covino John Reinhard Dorith Wunnicke Inga Hänelt Ilya Levental Gerhard Hummer Robert Ernst
author_facet	Stephanie Ballweg Erdinc Sezgin Milka Doktorova Roberto Covino John Reinhard Dorith Wunnicke Inga Hänelt Ilya Levental Gerhard Hummer Robert Ernst
author_sort	Stephanie Ballweg
title	Regulation of lipid saturation without sensing membrane fluidity
title_short	Regulation of lipid saturation without sensing membrane fluidity
title_full	Regulation of lipid saturation without sensing membrane fluidity
title_fullStr	Regulation of lipid saturation without sensing membrane fluidity
title_full_unstemmed	Regulation of lipid saturation without sensing membrane fluidity
title_sort	regulation of lipid saturation without sensing membrane fluidity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7183c9c33c7245fcb2bcf9a185481273
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Regulation of lipid saturation without sensing membrane fluidity

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