Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice

Tanycytes contribute to the regulation of multiple hypothalamic functions. Here the authors investigate the regenerative and tumorigenic potential of adult Rax+ tanycytes in the median eminence in the context of the stem cell niche in mice.

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Autores principales: Wenhui Mu, Si Li, Jingkai Xu, Xize Guo, Haoda Wu, Zhenhua Chen, Lianyong Qiao, Gisela Helfer, Falong Lu, Chong Liu, Qing-Feng Wu
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7185e847c5dc45ee9933ecec9e5d5d77
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spelling oai:doaj.org-article:7185e847c5dc45ee9933ecec9e5d5d772021-12-02T15:51:01ZHypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice10.1038/s41467-021-22640-z2041-1723https://doaj.org/article/7185e847c5dc45ee9933ecec9e5d5d772021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22640-zhttps://doaj.org/toc/2041-1723Tanycytes contribute to the regulation of multiple hypothalamic functions. Here the authors investigate the regenerative and tumorigenic potential of adult Rax+ tanycytes in the median eminence in the context of the stem cell niche in mice.Wenhui MuSi LiJingkai XuXize GuoHaoda WuZhenhua ChenLianyong QiaoGisela HelferFalong LuChong LiuQing-Feng WuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Wenhui Mu
Si Li
Jingkai Xu
Xize Guo
Haoda Wu
Zhenhua Chen
Lianyong Qiao
Gisela Helfer
Falong Lu
Chong Liu
Qing-Feng Wu
Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
description Tanycytes contribute to the regulation of multiple hypothalamic functions. Here the authors investigate the regenerative and tumorigenic potential of adult Rax+ tanycytes in the median eminence in the context of the stem cell niche in mice.
format article
author Wenhui Mu
Si Li
Jingkai Xu
Xize Guo
Haoda Wu
Zhenhua Chen
Lianyong Qiao
Gisela Helfer
Falong Lu
Chong Liu
Qing-Feng Wu
author_facet Wenhui Mu
Si Li
Jingkai Xu
Xize Guo
Haoda Wu
Zhenhua Chen
Lianyong Qiao
Gisela Helfer
Falong Lu
Chong Liu
Qing-Feng Wu
author_sort Wenhui Mu
title Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
title_short Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
title_full Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
title_fullStr Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
title_full_unstemmed Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
title_sort hypothalamic rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7185e847c5dc45ee9933ecec9e5d5d77
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