Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019

Objective. This study intends to analyze the data of fungemia in a large tertiary hospital from 2010 to 2019, and is aimed at understanding its epidemic characteristics and drug resistance. Methods. The “Hospital Infection Real-Time Monitoring System” was used to retrieve the case information of pat...

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Autores principales:	Yanling Bai, Zhigang Zheng, Ting Liu, Zhongqiang Yan, Mingmei Du, Hongwu Yao, Yunxi Liu, Jijiang Suo
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/718832a14e4640cf938cb95edfdf5e4f
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spelling	oai:doaj.org-article:718832a14e4640cf938cb95edfdf5e4f2021-11-15T01:18:58ZEpidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 20192314-614110.1155/2021/2529171https://doaj.org/article/718832a14e4640cf938cb95edfdf5e4f2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2529171https://doaj.org/toc/2314-6141Objective. This study intends to analyze the data of fungemia in a large tertiary hospital from 2010 to 2019, and is aimed at understanding its epidemic characteristics and drug resistance. Methods. The “Hospital Infection Real-Time Monitoring System” was used to retrieve the case information of patients who were hospitalized for more than 48 hours from 2010 to 2019. The questionnaire was designed to collect patients’ basic information, infection situation, drug resistance, and other related information. Statistical software was used for analysis. Results. The fungi detection rate was in the range of 0.19%~0.75% in ten years, the average rate was 0.29%, and the rate 0.2%~0.3% since 2013, which was lower than that from 2010 to 2012. Non-Candida albicans was the main fungus, accounting for 62.50%. The drug resistance of non-C. albicans was higher than that of C. albicans, among which C. glabrata had the highest resistance rate. Data analysis showed that the patients with more serious basic diseases, combined with infection of other sites, surgery, long hospital stay, combination of antibiotics, and invasive catheterization, were more likely to occur fungemia. Conclusion. We should pay more attention to the patients with high-risk factors of fungemia and focus on the drug resistance of non-C. albicans, choose the right antifungal drugs, so as to improve the level of diagnosis and treatment.Yanling BaiZhigang ZhengTing LiuZhongqiang YanMingmei DuHongwu YaoYunxi LiuJijiang SuoHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Yanling Bai Zhigang Zheng Ting Liu Zhongqiang Yan Mingmei Du Hongwu Yao Yunxi Liu Jijiang Suo Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019
description	Objective. This study intends to analyze the data of fungemia in a large tertiary hospital from 2010 to 2019, and is aimed at understanding its epidemic characteristics and drug resistance. Methods. The “Hospital Infection Real-Time Monitoring System” was used to retrieve the case information of patients who were hospitalized for more than 48 hours from 2010 to 2019. The questionnaire was designed to collect patients’ basic information, infection situation, drug resistance, and other related information. Statistical software was used for analysis. Results. The fungi detection rate was in the range of 0.19%~0.75% in ten years, the average rate was 0.29%, and the rate 0.2%~0.3% since 2013, which was lower than that from 2010 to 2012. Non-Candida albicans was the main fungus, accounting for 62.50%. The drug resistance of non-C. albicans was higher than that of C. albicans, among which C. glabrata had the highest resistance rate. Data analysis showed that the patients with more serious basic diseases, combined with infection of other sites, surgery, long hospital stay, combination of antibiotics, and invasive catheterization, were more likely to occur fungemia. Conclusion. We should pay more attention to the patients with high-risk factors of fungemia and focus on the drug resistance of non-C. albicans, choose the right antifungal drugs, so as to improve the level of diagnosis and treatment.
format	article
author	Yanling Bai Zhigang Zheng Ting Liu Zhongqiang Yan Mingmei Du Hongwu Yao Yunxi Liu Jijiang Suo
author_facet	Yanling Bai Zhigang Zheng Ting Liu Zhongqiang Yan Mingmei Du Hongwu Yao Yunxi Liu Jijiang Suo
author_sort	Yanling Bai
title	Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019
title_short	Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019
title_full	Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019
title_fullStr	Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019
title_full_unstemmed	Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019
title_sort	epidemiological characteristics and drug resistance of fungemia in general hospitals from 2010 to 2019
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/718832a14e4640cf938cb95edfdf5e4f
work_keys_str_mv	AT yanlingbai epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT zhigangzheng epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT tingliu epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT zhongqiangyan epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT mingmeidu epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT hongwuyao epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT yunxiliu epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019 AT jijiangsuo epidemiologicalcharacteristicsanddrugresistanceoffungemiaingeneralhospitalsfrom2010to2019
_version_	1718428991760629760

Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019

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