Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients

Abstract Cone-beam computed tomography (CBCT) integrated with a linear accelerator is widely used to increase the accuracy of radiotherapy and plays an important role in image-guided radiotherapy (IGRT). For comparison with fan-beam computed tomography (FBCT), the image quality of CBCT is indistinct...

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Autores principales: Hui-Ju Tien, Hsin-Chih Yang, Pei-Wei Shueng, Jyh-Cheng Chen
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/718d6a340dc8497e9f1128a01ff09a5d
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spelling oai:doaj.org-article:718d6a340dc8497e9f1128a01ff09a5d2021-12-02T14:01:25ZCone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients10.1038/s41598-020-80803-22045-2322https://doaj.org/article/718d6a340dc8497e9f1128a01ff09a5d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80803-2https://doaj.org/toc/2045-2322Abstract Cone-beam computed tomography (CBCT) integrated with a linear accelerator is widely used to increase the accuracy of radiotherapy and plays an important role in image-guided radiotherapy (IGRT). For comparison with fan-beam computed tomography (FBCT), the image quality of CBCT is indistinct due to X-ray scattering, noise, and artefacts. We proposed a deep learning model, “Cycle-Deblur GAN”, combined with CycleGAN and Deblur-GAN models to improve the image quality of chest CBCT images. The 8706 CBCT and FBCT image pairs were used for training, and 1150 image pairs were used for testing in deep learning. The generated CBCT images from the Cycle-Deblur GAN model demonstrated closer CT values to FBCT in the lung, breast, mediastinum, and sternum compared to the CycleGAN and RED-CNN models. The quantitative evaluations of MAE, PSNR, and SSIM for CBCT generated from the Cycle-Deblur GAN model demonstrated better results than the CycleGAN and RED-CNN models. The Cycle-Deblur GAN model improved image quality and CT-value accuracy and preserved structural details for chest CBCT images.Hui-Ju TienHsin-Chih YangPei-Wei ShuengJyh-Cheng ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Hui-Ju Tien
Hsin-Chih Yang
Pei-Wei Shueng
Jyh-Cheng Chen
Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
description Abstract Cone-beam computed tomography (CBCT) integrated with a linear accelerator is widely used to increase the accuracy of radiotherapy and plays an important role in image-guided radiotherapy (IGRT). For comparison with fan-beam computed tomography (FBCT), the image quality of CBCT is indistinct due to X-ray scattering, noise, and artefacts. We proposed a deep learning model, “Cycle-Deblur GAN”, combined with CycleGAN and Deblur-GAN models to improve the image quality of chest CBCT images. The 8706 CBCT and FBCT image pairs were used for training, and 1150 image pairs were used for testing in deep learning. The generated CBCT images from the Cycle-Deblur GAN model demonstrated closer CT values to FBCT in the lung, breast, mediastinum, and sternum compared to the CycleGAN and RED-CNN models. The quantitative evaluations of MAE, PSNR, and SSIM for CBCT generated from the Cycle-Deblur GAN model demonstrated better results than the CycleGAN and RED-CNN models. The Cycle-Deblur GAN model improved image quality and CT-value accuracy and preserved structural details for chest CBCT images.
format article
author Hui-Ju Tien
Hsin-Chih Yang
Pei-Wei Shueng
Jyh-Cheng Chen
author_facet Hui-Ju Tien
Hsin-Chih Yang
Pei-Wei Shueng
Jyh-Cheng Chen
author_sort Hui-Ju Tien
title Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
title_short Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
title_full Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
title_fullStr Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
title_full_unstemmed Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
title_sort cone-beam ct image quality improvement using cycle-deblur consistent adversarial networks (cycle-deblur gan) for chest ct imaging in breast cancer patients
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/718d6a340dc8497e9f1128a01ff09a5d
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AT hsinchihyang conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients
AT peiweishueng conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients
AT jyhchengchen conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients
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