Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients
Abstract Cone-beam computed tomography (CBCT) integrated with a linear accelerator is widely used to increase the accuracy of radiotherapy and plays an important role in image-guided radiotherapy (IGRT). For comparison with fan-beam computed tomography (FBCT), the image quality of CBCT is indistinct...
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2021
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oai:doaj.org-article:718d6a340dc8497e9f1128a01ff09a5d2021-12-02T14:01:25ZCone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients10.1038/s41598-020-80803-22045-2322https://doaj.org/article/718d6a340dc8497e9f1128a01ff09a5d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-80803-2https://doaj.org/toc/2045-2322Abstract Cone-beam computed tomography (CBCT) integrated with a linear accelerator is widely used to increase the accuracy of radiotherapy and plays an important role in image-guided radiotherapy (IGRT). For comparison with fan-beam computed tomography (FBCT), the image quality of CBCT is indistinct due to X-ray scattering, noise, and artefacts. We proposed a deep learning model, “Cycle-Deblur GAN”, combined with CycleGAN and Deblur-GAN models to improve the image quality of chest CBCT images. The 8706 CBCT and FBCT image pairs were used for training, and 1150 image pairs were used for testing in deep learning. The generated CBCT images from the Cycle-Deblur GAN model demonstrated closer CT values to FBCT in the lung, breast, mediastinum, and sternum compared to the CycleGAN and RED-CNN models. The quantitative evaluations of MAE, PSNR, and SSIM for CBCT generated from the Cycle-Deblur GAN model demonstrated better results than the CycleGAN and RED-CNN models. The Cycle-Deblur GAN model improved image quality and CT-value accuracy and preserved structural details for chest CBCT images.Hui-Ju TienHsin-Chih YangPei-Wei ShuengJyh-Cheng ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021) |
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Medicine R Science Q Hui-Ju Tien Hsin-Chih Yang Pei-Wei Shueng Jyh-Cheng Chen Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients |
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Abstract Cone-beam computed tomography (CBCT) integrated with a linear accelerator is widely used to increase the accuracy of radiotherapy and plays an important role in image-guided radiotherapy (IGRT). For comparison with fan-beam computed tomography (FBCT), the image quality of CBCT is indistinct due to X-ray scattering, noise, and artefacts. We proposed a deep learning model, “Cycle-Deblur GAN”, combined with CycleGAN and Deblur-GAN models to improve the image quality of chest CBCT images. The 8706 CBCT and FBCT image pairs were used for training, and 1150 image pairs were used for testing in deep learning. The generated CBCT images from the Cycle-Deblur GAN model demonstrated closer CT values to FBCT in the lung, breast, mediastinum, and sternum compared to the CycleGAN and RED-CNN models. The quantitative evaluations of MAE, PSNR, and SSIM for CBCT generated from the Cycle-Deblur GAN model demonstrated better results than the CycleGAN and RED-CNN models. The Cycle-Deblur GAN model improved image quality and CT-value accuracy and preserved structural details for chest CBCT images. |
format |
article |
author |
Hui-Ju Tien Hsin-Chih Yang Pei-Wei Shueng Jyh-Cheng Chen |
author_facet |
Hui-Ju Tien Hsin-Chih Yang Pei-Wei Shueng Jyh-Cheng Chen |
author_sort |
Hui-Ju Tien |
title |
Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients |
title_short |
Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients |
title_full |
Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients |
title_fullStr |
Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients |
title_full_unstemmed |
Cone-beam CT image quality improvement using Cycle-Deblur consistent adversarial networks (Cycle-Deblur GAN) for chest CT imaging in breast cancer patients |
title_sort |
cone-beam ct image quality improvement using cycle-deblur consistent adversarial networks (cycle-deblur gan) for chest ct imaging in breast cancer patients |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/718d6a340dc8497e9f1128a01ff09a5d |
work_keys_str_mv |
AT huijutien conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients AT hsinchihyang conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients AT peiweishueng conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients AT jyhchengchen conebeamctimagequalityimprovementusingcycledeblurconsistentadversarialnetworkscycledeblurganforchestctimaginginbreastcancerpatients |
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