Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium.

Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium.

<h4>Background</h4>During transendothelial migration, leukocytes use adhesion molecules, such as ICAM-1, to adhere to the endothelium. ICAM-1 is a dynamic molecule that is localized in the apical membrane of the endothelium and clusters upon binding to leukocytes. However, not much is kn...

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Autores principales: Jaap D van Buul, Jos van Rijssel, Floris P J van Alphen, Mark Hoogenboezem, Simon Tol, Kees A Hoeben, Jan van Marle, Erik P J Mul, Peter L Hordijk
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/7193af2812dc4e36a4aa181fd4b28836
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