Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.
To be able to colonize its host, invading Salmonella enterica serovar Typhimurium must disrupt and severely affect host-microbiome homeostasis. Here we report that S. Typhimurium induces acute infectious colitis by inhibiting peroxisome proliferator-activated receptor gamma (PPARγ) expression in int...
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Autores principales: | Parag Kundu, Teo Wei Ling, Agata Korecka, Yinghui Li, Rossana D'Arienzo, Ralph M Bunte, Thorsten Berger, Velmurugesan Arulampalam, Pierre Chambon, Tak Wah Mak, Walter Wahli, Sven Pettersson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/719b25472c0349cc8db7b99bc10a3ec6 |
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