Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea
Introduction: Calotropis is a member of the milkweed or Asclepiadeae family. The latex of Calotropis gigantea (C gigantea) contains cardiac glycosides, fatty acids and calcium oxalate. The sap of Calotropis procera (C procera) produces acidic latex. Toxic effect of latex manifests after a few ho...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
JCDR Research and Publications Private Limited
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/71a892566c9e441d8cf1ea1664bf6f58 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:71a892566c9e441d8cf1ea1664bf6f58 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:71a892566c9e441d8cf1ea1664bf6f582021-11-11T10:24:24ZOcular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea10.7860/JCDR/2021/49510.153342249-782X0973-709Xhttps://doaj.org/article/71a892566c9e441d8cf1ea1664bf6f582021-09-01T00:00:00Zhttps://www.jcdr.net/articles/PDF/15334/49510_CE[Ra1]_F[SK]_PF1(AKA_RK)_PFA(AKA_KM)_PN(KM).pdfhttps://doaj.org/toc/2249-782Xhttps://doaj.org/toc/0973-709XIntroduction: Calotropis is a member of the milkweed or Asclepiadeae family. The latex of Calotropis gigantea (C gigantea) contains cardiac glycosides, fatty acids and calcium oxalate. The sap of Calotropis procera (C procera) produces acidic latex. Toxic effect of latex manifests after a few hours with diminution of vision due to corneal oedema with folds in Descemet’s membrane. Aim: To evaluate the ocular toxicity by the latex of calotropis procera and calotropis gigantea due to accidental exposure. Materials and Methods: This was a prospective observational study conducted for a duration of six months (September 2018 to February 2019) on 18 patients with alleged accidental exposure to calotropis latex. The patients were examined in the Department of Ophthalmology, Mandya Institute of Medical Sciences (MIMS), Mandya, Karnataka, India. After a thorough saline wash under topical anaesthesia, visual acuity was measured by using Snellen’s chart, then patients were subjected for slit lamp biomicroscopy examination, Intraocular Pressure (IOP) measurement and undilated fundus examination and the findings were noted. Demographic details like age and sex, activity at time of injury, mode of injury were noted and follow-up was done for a period of 30 days. Data were analysed using Epi info software and descriptive statistics like mean and percentage were calculated. Results: Total 18 patients reported with calotropis associated eye toxicity, among which 11 (61.1%) were of C gigantea and seven (38.9%) were of C procera. Out of total, seven (38.9%) were males and 11 (61.1%) females. A total of 14 (77.8%) patients presented within 24 hours of injury. Eleven (61.1%) patients had involvement of both the eyes. The main symptoms were burning, irritation, foreign body sensation and diminution of vision. Best Corrected Visual Acuity (BCVA) varied from 6/9 to 6/60. Corneal oedema or striate keratopathy was the most common sign. Corneal oedema resolved in one week in case of C procera with use of topical corticosteroids except in three cases of C gigantea which took two weeks. Conclusion: C procera and C gigantea causes significant corneal oedema and ocular morbidity. By simple health education and occupational precaution, we can prevent ocular morbidity. Shruthi amalagondhi manjunathapradeep addagadde venkataramanaRajshekarsrinivas siddegowdaJCDR Research and Publications Private Limitedarticlechemical injurycorneal oedemastriate keratopathyMedicineRENJournal of Clinical and Diagnostic Research, Vol 15, Iss 9, Pp NC05-NC08 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
chemical injury corneal oedema striate keratopathy Medicine R |
| spellingShingle |
chemical injury corneal oedema striate keratopathy Medicine R Shruthi amalagondhi manjunatha pradeep addagadde venkataramana Rajshekar srinivas siddegowda Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea |
| description |
Introduction: Calotropis is a member of the milkweed or
Asclepiadeae family. The latex of Calotropis gigantea (C gigantea)
contains cardiac glycosides, fatty acids and calcium oxalate. The
sap of Calotropis procera (C procera) produces acidic latex. Toxic
effect of latex manifests after a few hours with diminution of vision
due to corneal oedema with folds in Descemet’s membrane.
Aim: To evaluate the ocular toxicity by the latex of calotropis
procera and calotropis gigantea due to accidental exposure.
Materials and Methods: This was a prospective observational
study conducted for a duration of six months (September 2018
to February 2019) on 18 patients with alleged accidental exposure
to calotropis latex. The patients were examined in the Department
of Ophthalmology, Mandya Institute of Medical Sciences (MIMS),
Mandya, Karnataka, India. After a thorough saline wash under
topical anaesthesia, visual acuity was measured by using Snellen’s
chart, then patients were subjected for slit lamp biomicroscopy
examination, Intraocular Pressure (IOP) measurement and undilated
fundus examination and the findings were noted. Demographic
details like age and sex, activity at time of injury, mode of injury
were noted and follow-up was done for a period of 30 days. Data
were analysed using Epi info software and descriptive statistics
like mean and percentage were calculated.
Results: Total 18 patients reported with calotropis associated
eye toxicity, among which 11 (61.1%) were of C gigantea and
seven (38.9%) were of C procera. Out of total, seven (38.9%)
were males and 11 (61.1%) females. A total of 14 (77.8%) patients
presented within 24 hours of injury. Eleven (61.1%) patients had
involvement of both the eyes. The main symptoms were burning,
irritation, foreign body sensation and diminution of vision. Best
Corrected Visual Acuity (BCVA) varied from 6/9 to 6/60. Corneal
oedema or striate keratopathy was the most common sign.
Corneal oedema resolved in one week in case of C procera with
use of topical corticosteroids except in three cases of C gigantea
which took two weeks.
Conclusion: C procera and C gigantea causes significant corneal
oedema and ocular morbidity. By simple health education and
occupational precaution, we can prevent ocular morbidity. |
| format |
article |
| author |
Shruthi amalagondhi manjunatha pradeep addagadde venkataramana Rajshekar srinivas siddegowda |
| author_facet |
Shruthi amalagondhi manjunatha pradeep addagadde venkataramana Rajshekar srinivas siddegowda |
| author_sort |
Shruthi amalagondhi manjunatha |
| title |
Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea |
| title_short |
Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea |
| title_full |
Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea |
| title_fullStr |
Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea |
| title_full_unstemmed |
Ocular Toxicity due to Accidental Exposure to Plant Latex by Calotropis procera and Calotropis gigantea |
| title_sort |
ocular toxicity due to accidental exposure to plant latex by calotropis procera and calotropis gigantea |
| publisher |
JCDR Research and Publications Private Limited |
| publishDate |
2021 |
| url |
https://doaj.org/article/71a892566c9e441d8cf1ea1664bf6f58 |
| work_keys_str_mv |
AT shruthiamalagondhimanjunatha oculartoxicityduetoaccidentalexposuretoplantlatexbycalotropisproceraandcalotropisgigantea AT pradeepaddagaddevenkataramana oculartoxicityduetoaccidentalexposuretoplantlatexbycalotropisproceraandcalotropisgigantea AT rajshekar oculartoxicityduetoaccidentalexposuretoplantlatexbycalotropisproceraandcalotropisgigantea AT srinivassiddegowda oculartoxicityduetoaccidentalexposuretoplantlatexbycalotropisproceraandcalotropisgigantea |
| _version_ |
1718439135689048064 |