The Effect of Associated Vascular Injuries in Penetrating Trauma to the Duodenum and Pancreas
Objectives: Major vascular injuries contribute significantly to the mortality of pancreatic and duodenal trauma. We hypothesizedthat in the setting of penetrating trauma to the pancreas and/or duodenum, independent predictors of mortality associated withvascular injuries could be identified. Our obj...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Shiraz University of Medical Sciences
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/71ab4c298fb14f0f8d5da4e862274302 |
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| Sumario: | Objectives: Major vascular injuries contribute significantly to the mortality of pancreatic and duodenal trauma. We hypothesizedthat in the setting of penetrating trauma to the pancreas and/or duodenum, independent predictors of mortality associated withvascular injuries could be identified. Our objectives in this study were to describe the national profile of major vascular injuries aswell as to identify predictors of morbidity and mortality.Methods: Using the abbreviated injury scale 2005 and ICD-9-CM E-codes, we identified 597 penetrating pancreatic, duodenal, andpancreaticoduodenal trauma patients with major vascular injuries from the NTDB between 2010 and 2014. We controlled patientlevelcovariates of age, biological sex, systolic blood pressure (SBP), Glasgow coma score (GCS), pulse, injury severity score (ISS), andorgan injury scale (OIS) grade. We estimated multivariable generalized linear mixed models to account for the nesting of patientswithin trauma centers.Results: Our results indicated an overall mortality rate of 26.1%. Approximately 19% of patients died within 24 hours of admission,and of those, 78% died in the first 6 hours. The inferior vena cava was the most commonly injured vessel. The average number ofassociated injuries was 4.9 in pancreatic or duodenal trauma and 5.4 in pancreaticoduodenal. Statistically significant independentpredictors of mortality were firearm mechanism, SBP, GCS, and pulse. Specifically, odds of death were decreased with a 10-mmHghigher admission SBP (7.7% decreased odds), one-point higher GCS (12.8%), and a 10-beat lower pulse (11.6%).Conclusions: This study is the first to examine the effect of major vascular injuries in the setting of penetrating trauma to thepancreas and/or duodenum utilizing the NTDB.We have identified patterns of injury and statistically significant independent predictorsof morbidity and mortality. |
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