RNA structure-wide discovery of functional interactions with multiplexed RNA motif library

Structured RNA motifs can be obtained by structure probing, duplex capture, and motif prediction. Here the authors develop a multiplexed affinity assay system to identify functional protein interactors from an RNA structure library with validated or predicted RNA motifs.

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Autores principales:	Kaoru R. Komatsu, Toshiki Taya, Sora Matsumoto, Emi Miyashita, Shunnichi Kashida, Hirohide Saito
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/71ac6f2904824fc8bf435fd6f84ffb58
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spelling	oai:doaj.org-article:71ac6f2904824fc8bf435fd6f84ffb582021-12-02T14:16:24ZRNA structure-wide discovery of functional interactions with multiplexed RNA motif library10.1038/s41467-020-19699-52041-1723https://doaj.org/article/71ac6f2904824fc8bf435fd6f84ffb582020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19699-5https://doaj.org/toc/2041-1723Structured RNA motifs can be obtained by structure probing, duplex capture, and motif prediction. Here the authors develop a multiplexed affinity assay system to identify functional protein interactors from an RNA structure library with validated or predicted RNA motifs.Kaoru R. KomatsuToshiki TayaSora MatsumotoEmi MiyashitaShunnichi KashidaHirohide SaitoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kaoru R. Komatsu Toshiki Taya Sora Matsumoto Emi Miyashita Shunnichi Kashida Hirohide Saito RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
description	Structured RNA motifs can be obtained by structure probing, duplex capture, and motif prediction. Here the authors develop a multiplexed affinity assay system to identify functional protein interactors from an RNA structure library with validated or predicted RNA motifs.
format	article
author	Kaoru R. Komatsu Toshiki Taya Sora Matsumoto Emi Miyashita Shunnichi Kashida Hirohide Saito
author_facet	Kaoru R. Komatsu Toshiki Taya Sora Matsumoto Emi Miyashita Shunnichi Kashida Hirohide Saito
author_sort	Kaoru R. Komatsu
title	RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
title_short	RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
title_full	RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
title_fullStr	RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
title_full_unstemmed	RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
title_sort	rna structure-wide discovery of functional interactions with multiplexed rna motif library
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/71ac6f2904824fc8bf435fd6f84ffb58
work_keys_str_mv	AT kaorurkomatsu rnastructurewidediscoveryoffunctionalinteractionswithmultiplexedrnamotiflibrary AT toshikitaya rnastructurewidediscoveryoffunctionalinteractionswithmultiplexedrnamotiflibrary AT soramatsumoto rnastructurewidediscoveryoffunctionalinteractionswithmultiplexedrnamotiflibrary AT emimiyashita rnastructurewidediscoveryoffunctionalinteractionswithmultiplexedrnamotiflibrary AT shunnichikashida rnastructurewidediscoveryoffunctionalinteractionswithmultiplexedrnamotiflibrary AT hirohidesaito rnastructurewidediscoveryoffunctionalinteractionswithmultiplexedrnamotiflibrary
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RNA structure-wide discovery of functional interactions with multiplexed RNA motif library

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