A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates

Polyfluorinated hexopyranoses display unique physical, chemical and biological properties, however their stereoselective synthesis is highly challenging. Here, the authors report a synthetic approach based on the chemical manipulation of inexpensive levoglucosan to obtain heavily fluorinated monosac...

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Autores principales: Vincent Denavit, Danny Lainé, Jacob St-Gelais, Paul A. Johnson, Denis Giguère
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/71b3d4d6b81340a39a931d5a0fa20843
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spelling oai:doaj.org-article:71b3d4d6b81340a39a931d5a0fa208432021-12-02T17:31:14ZA Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates10.1038/s41467-018-06901-y2041-1723https://doaj.org/article/71b3d4d6b81340a39a931d5a0fa208432018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06901-yhttps://doaj.org/toc/2041-1723Polyfluorinated hexopyranoses display unique physical, chemical and biological properties, however their stereoselective synthesis is highly challenging. Here, the authors report a synthetic approach based on the chemical manipulation of inexpensive levoglucosan to obtain heavily fluorinated monosaccharides stereoselectively.Vincent DenavitDanny LainéJacob St-GelaisPaul A. JohnsonDenis GiguèreNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vincent Denavit
Danny Lainé
Jacob St-Gelais
Paul A. Johnson
Denis Giguère
A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
description Polyfluorinated hexopyranoses display unique physical, chemical and biological properties, however their stereoselective synthesis is highly challenging. Here, the authors report a synthetic approach based on the chemical manipulation of inexpensive levoglucosan to obtain heavily fluorinated monosaccharides stereoselectively.
format article
author Vincent Denavit
Danny Lainé
Jacob St-Gelais
Paul A. Johnson
Denis Giguère
author_facet Vincent Denavit
Danny Lainé
Jacob St-Gelais
Paul A. Johnson
Denis Giguère
author_sort Vincent Denavit
title A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
title_short A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
title_full A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
title_fullStr A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
title_full_unstemmed A Chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
title_sort chiron approach towards the stereoselective synthesis of polyfluorinated carbohydrates
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/71b3d4d6b81340a39a931d5a0fa20843
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