LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis

LRPPRC regulates redox homeostasis via the circANKHD1/FOXM1 axis to enhance bladder urothelial carcinoma tumorigenesis

Reactive oxygen species (ROS) which are continuously generated mainly by mitochondria, have been proved to play an important role in the stress signaling of cancer cells. Moreover, pentatricopeptide repeat (PPR) proteins have been suggested to take part in mitochondrial metabolism. However, the mech...

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Détails bibliographiques
Auteurs principaux: Wen-Su Wei, Ning Wang, Min-hua Deng, Pei Dong, Jian-ye Liu, Zhen Xiang, Xiang-Dong Li, Zhi-yong Li, Zhen-hua Liu, Yu-lu Peng, Zhen Li, Li-Juan Jiang, Kai Yao, Yun-lin Ye, Wen-hua Lu, Zhi-Ling Zhang, Fang-Jian Zhou, Zhuo-Wei Liu, Dan Xie, Chun-ping Yu
Format: article
Langue:EN
Publié: Elsevier 2021
Sujets:
Urothelial carcinoma of the bladder
LRPPRC
circRNA
FOXM1
ROS
Medicine (General)
R5-920
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/71b4bfd3811c4c2c8cef0c6e2fea7100
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https://doaj.org/article/71b4bfd3811c4c2c8cef0c6e2fea7100

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