ISGylation in Innate Antiviral Immunity and Pathogen Defense Responses: A Review

The interferon-stimulating gene 15 (ISG15) protein is a ubiquitin-like protein induced by interferons or pathogens. ISG15 can exist in free form or covalently bind to the target protein through an enzymatic cascade reaction, which is called ISGylation. ISGylation has been found to play an important...

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Main Authors: Mengdi Zhang, Jingxian Li, Haiyan Yan, Jun Huang, Fangwei Wang, Ting Liu, Linghui Zeng, Fangfang Zhou
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/71ba5d0e54504193a235617492e975c4
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