Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1
Cas9 and Cpf1 have both been adapted for genome engineering, editing and gene expression regulation. Here the authors design a fusion guide RNA that can interact with both proteins for multiple and orthogonal genome manipulation.
Guardado en:
Autores principales: | Jiyeon Kweon, An-Hee Jang, Da-eun Kim, Jin Wook Yang, Mijung Yoon, Ha Rim Shin, Jin-Soo Kim, Yongsub Kim |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/71bb17bf76e3494bae0588923dad639c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Publisher Correction: Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1
por: Jiyeon Kweon, et al.
Publicado: (2018) -
Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
por: Youngbin Lim, et al.
Publicado: (2016) -
Genome-wide specificity of dCpf1 cytidine base editors
por: Daesik Kim, et al.
Publicado: (2020) -
CRISPR/Cpf1-mediated DNA-free plant genome editing
por: Hyeran Kim, et al.
Publicado: (2017) -
CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration
por: Taeyoung Koo, et al.
Publicado: (2018)