Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation

Inhibition of Vascular Smooth Muscle and Cancer Cell Proliferation by New VEGFR Inhibitors and Their Immunomodulator Effect: Design, Synthesis, and Biological Evaluation

Abnormal vascular smooth muscle cell (VSMC) proliferation has an important role in the pathogenesis of both atherosclerosis restenosis and hypertension. Vascular endothelial growth factor (VEGF) has been shown to stimulate VSMC proliferation. In addition, angiogenesis is one of the hallmarks of canc...

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Autores principales: Feng Ran, Wendong Li, Yi Qin, Tong Yu, Zhao Liu, Min Zhou, Cheng Liu, Tong Qiao, Xiaoqiang Li, Reda G. Yousef, Ibrahim H. Eissa, Mohamed M. Khalifa
Formato: article
Lenguaje:EN
Publicado: Hindawi Limited 2021
Materias:
Cytology
QH573-671
Acceso en línea:https://doaj.org/article/71c7bb63087547aab732fa0d1750f407
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