Dopamine D2 receptor regulates cortical synaptic pruning in rodents

Dopamine D2 receptor regulates cortical synaptic pruning in rodents

Synaptic pruning is important during development and synaptic plasticity. Here, the authors show that the dopamine D2 receptor (Drd2) in the anterior cingulate cortex regulates synaptic pruning, affecting LTD and behaviour in transgenic rats.

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Autores principales: Ya-Qiang Zhang, Wei-Peng Lin, Li-Ping Huang, Bing Zhao, Cheng-Cheng Zhang, Dong-Min Yin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/71c8769e016b48e790411f315415d656
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