Dopamine D2 receptor regulates cortical synaptic pruning in rodents

Synaptic pruning is important during development and synaptic plasticity. Here, the authors show that the dopamine D2 receptor (Drd2) in the anterior cingulate cortex regulates synaptic pruning, affecting LTD and behaviour in transgenic rats.

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Bibliographic Details
Main Authors: Ya-Qiang Zhang, Wei-Peng Lin, Li-Ping Huang, Bing Zhao, Cheng-Cheng Zhang, Dong-Min Yin
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/71c8769e016b48e790411f315415d656
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