Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study
Victorine Raïssa Ngo Nkondjock1 1, Thérèse Martin Cheteu Wabo1 1, Janet Cheruiyot Kosgey2 2, Yunlong Zhang1 1, Daniel Adjei Amporfro3 3, Humara Adnan4 4, Imran Shah1 1, Ying Li1 1 1Department of Nutrition and Food Hygiene, The National Key Discipline, School of Public Health, Harbin Medical Universi...
Guardado en:
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/71cd0df54c55456197b57e097fa6f6a4 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:71cd0df54c55456197b57e097fa6f6a4 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:71cd0df54c55456197b57e097fa6f6a42021-12-02T17:55:06ZInsulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study1178-7007https://doaj.org/article/71cd0df54c55456197b57e097fa6f6a42021-07-01T00:00:00Zhttps://www.dovepress.com/insulin-resistance-serum-calcium-and-hypertension-a-cross-sectional-st-peer-reviewed-fulltext-article-DMSOhttps://doaj.org/toc/1178-7007Victorine Raïssa Ngo Nkondjock1 1, Thérèse Martin Cheteu Wabo1 1, Janet Cheruiyot Kosgey2 2, Yunlong Zhang1 1, Daniel Adjei Amporfro3 3, Humara Adnan4 4, Imran Shah1 1, Ying Li1 1 1Department of Nutrition and Food Hygiene, The National Key Discipline, School of Public Health, Harbin Medical University, Harbin, People’s Republic of China; 2School of Biological Science, Technical University of Kenya, Nairobi, Kenya; 3Department of Social Medicine and Health Services Management, School of Public Health, Harbin Medical University, Harbin, People’s Republic of China; 4Department of Biostatistics and Epidemiology, School of Public Health, Harbin Medical University, Harbin, People’s Republic of ChinaCorrespondence: Ying LiDepartment of Nutrition and Food Hygiene, 157 Baojian Road, Harbin, 150081, People’s Republic of ChinaTel +86-451-87502731Email liying_helen@163.comBackground: Recent research suggests the need to assess more ethnic disparities in hypertension (HTN). On the other hand, studies reveal impressive mortality rates due to cardiovascular diseases for some race and ethnic groups compared to others.Methods: We referred to a recent study on serum calcium (SC) and insulin resistance associated with HTN incidence to compare different race groups in the latter found relationship. We compare the current study outcomes with those from the Wu et al study.Results: From 425 participants of the National Health and Nutrition Examination Survey (NHANES) data, we found a significant association between race and hypertension; Cramer’s V (0.006) = 0.21 when adjusted with non-hypertensives and hypertensives. Mc Auley index (McA) was negatively related to hypertension, r (355) = − 0.24, p < 0.0001. SC associated with HTN in all race groups significance persisted only in non-Hispanic Whites after multivariate adjustments R2 of 74.1 (p = 0.03). McA was a mediator on SC-HTN in non-Hispanic Whites (NHW) (CoefIE = 13.25, [CI] = 1.42– 32.13), and a moderator in other Hispanics interaction (0.04) = 0.27 and NHW interaction (0.001) = 0.028.Conclusion: SC was associated with hypertension, similarly to the baseline study. SC and HTN association persisted in NHW compared to other race groups. Homeostasis model assessment (HOMA-IR) was not a mediator on SC-HTN, but with McA, this in NHW only. McA played a moderator role in OH and NHW. We suggest that race is a factor implicated in our findings, which may be investigated further in future research.Keywords: Mc Auley index, HOMA-IR, serum calcium, hypertension incidence, ethnicityNgo Nkondjock VRCheteu Wabo TMKosgey JCZhang YAdjei Amporfro DAdnan HShah ILi YDove Medical Pressarticlemc auley indexhoma-irserum calciumhypertension incidenceethnicitySpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 14, Pp 3361-3373 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
mc auley index homa-ir serum calcium hypertension incidence ethnicity Specialties of internal medicine RC581-951 |
| spellingShingle |
mc auley index homa-ir serum calcium hypertension incidence ethnicity Specialties of internal medicine RC581-951 Ngo Nkondjock VR Cheteu Wabo TM Kosgey JC Zhang Y Adjei Amporfro D Adnan H Shah I Li Y Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study |
| description |
Victorine Raïssa Ngo Nkondjock1 1, Thérèse Martin Cheteu Wabo1 1, Janet Cheruiyot Kosgey2 2, Yunlong Zhang1 1, Daniel Adjei Amporfro3 3, Humara Adnan4 4, Imran Shah1 1, Ying Li1 1 1Department of Nutrition and Food Hygiene, The National Key Discipline, School of Public Health, Harbin Medical University, Harbin, People’s Republic of China; 2School of Biological Science, Technical University of Kenya, Nairobi, Kenya; 3Department of Social Medicine and Health Services Management, School of Public Health, Harbin Medical University, Harbin, People’s Republic of China; 4Department of Biostatistics and Epidemiology, School of Public Health, Harbin Medical University, Harbin, People’s Republic of ChinaCorrespondence: Ying LiDepartment of Nutrition and Food Hygiene, 157 Baojian Road, Harbin, 150081, People’s Republic of ChinaTel +86-451-87502731Email liying_helen@163.comBackground: Recent research suggests the need to assess more ethnic disparities in hypertension (HTN). On the other hand, studies reveal impressive mortality rates due to cardiovascular diseases for some race and ethnic groups compared to others.Methods: We referred to a recent study on serum calcium (SC) and insulin resistance associated with HTN incidence to compare different race groups in the latter found relationship. We compare the current study outcomes with those from the Wu et al study.Results: From 425 participants of the National Health and Nutrition Examination Survey (NHANES) data, we found a significant association between race and hypertension; Cramer’s V (0.006) = 0.21 when adjusted with non-hypertensives and hypertensives. Mc Auley index (McA) was negatively related to hypertension, r (355) = − 0.24, p < 0.0001. SC associated with HTN in all race groups significance persisted only in non-Hispanic Whites after multivariate adjustments R2 of 74.1 (p = 0.03). McA was a mediator on SC-HTN in non-Hispanic Whites (NHW) (CoefIE = 13.25, [CI] = 1.42– 32.13), and a moderator in other Hispanics interaction (0.04) = 0.27 and NHW interaction (0.001) = 0.028.Conclusion: SC was associated with hypertension, similarly to the baseline study. SC and HTN association persisted in NHW compared to other race groups. Homeostasis model assessment (HOMA-IR) was not a mediator on SC-HTN, but with McA, this in NHW only. McA played a moderator role in OH and NHW. We suggest that race is a factor implicated in our findings, which may be investigated further in future research.Keywords: Mc Auley index, HOMA-IR, serum calcium, hypertension incidence, ethnicity |
| format |
article |
| author |
Ngo Nkondjock VR Cheteu Wabo TM Kosgey JC Zhang Y Adjei Amporfro D Adnan H Shah I Li Y |
| author_facet |
Ngo Nkondjock VR Cheteu Wabo TM Kosgey JC Zhang Y Adjei Amporfro D Adnan H Shah I Li Y |
| author_sort |
Ngo Nkondjock VR |
| title |
Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study |
| title_short |
Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study |
| title_full |
Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study |
| title_fullStr |
Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study |
| title_full_unstemmed |
Insulin Resistance, Serum Calcium and Hypertension: A Cross-Sectional Study of a Multiracial Population, and a Similarity Assessment of Results from a Single-Race Population’s Study |
| title_sort |
insulin resistance, serum calcium and hypertension: a cross-sectional study of a multiracial population, and a similarity assessment of results from a single-race population’s study |
| publisher |
Dove Medical Press |
| publishDate |
2021 |
| url |
https://doaj.org/article/71cd0df54c55456197b57e097fa6f6a4 |
| work_keys_str_mv |
AT ngonkondjockvr insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT cheteuwabotm insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT kosgeyjc insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT zhangy insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT adjeiamporfrod insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT adnanh insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT shahi insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy AT liy insulinresistanceserumcalciumandhypertensionacrosssectionalstudyofamultiracialpopulationandasimilarityassessmentofresultsfromasingleracepopulationrsquosstudy |
| _version_ |
1718379114854875136 |