In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons

The in vivo firing patterns of ventral midbrain dopamine neurons are controlled by afferent and intrinsic activity. The authors identified biophysical membrane potential signatures associated with distinct in vivo firing patterns in whole-cell recordings of spontaneously active midbrain dopamine neu...

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Autores principales: Kanako Otomo, Jessica Perkins, Anand Kulkarni, Strahinja Stojanovic, Jochen Roeper, Carlos A. Paladini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/71ce2d57d3964684b746a32f25f34cfc
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spelling oai:doaj.org-article:71ce2d57d3964684b746a32f25f34cfc2021-12-02T10:48:11ZIn vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons10.1038/s41467-020-20041-22041-1723https://doaj.org/article/71ce2d57d3964684b746a32f25f34cfc2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20041-2https://doaj.org/toc/2041-1723The in vivo firing patterns of ventral midbrain dopamine neurons are controlled by afferent and intrinsic activity. The authors identified biophysical membrane potential signatures associated with distinct in vivo firing patterns in whole-cell recordings of spontaneously active midbrain dopamine neurons.Kanako OtomoJessica PerkinsAnand KulkarniStrahinja StojanovicJochen RoeperCarlos A. PaladiniNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kanako Otomo
Jessica Perkins
Anand Kulkarni
Strahinja Stojanovic
Jochen Roeper
Carlos A. Paladini
In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
description The in vivo firing patterns of ventral midbrain dopamine neurons are controlled by afferent and intrinsic activity. The authors identified biophysical membrane potential signatures associated with distinct in vivo firing patterns in whole-cell recordings of spontaneously active midbrain dopamine neurons.
format article
author Kanako Otomo
Jessica Perkins
Anand Kulkarni
Strahinja Stojanovic
Jochen Roeper
Carlos A. Paladini
author_facet Kanako Otomo
Jessica Perkins
Anand Kulkarni
Strahinja Stojanovic
Jochen Roeper
Carlos A. Paladini
author_sort Kanako Otomo
title In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
title_short In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
title_full In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
title_fullStr In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
title_full_unstemmed In vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
title_sort in vivo patch-clamp recordings reveal distinct subthreshold signatures and threshold dynamics of midbrain dopamine neurons
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/71ce2d57d3964684b746a32f25f34cfc
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