DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination

DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.

Guardado en:
Detalles Bibliográficos
Autores principales: Prasun Chakraborty, Kevin Hiom
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/71d188e599e54f27b436ad5a2b697995
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:71d188e599e54f27b436ad5a2b697995
record_format dspace
spelling oai:doaj.org-article:71d188e599e54f27b436ad5a2b6979952021-12-02T15:23:19ZDHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination10.1038/s41467-021-24341-z2041-1723https://doaj.org/article/71d188e599e54f27b436ad5a2b6979952021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24341-zhttps://doaj.org/toc/2041-1723DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.Prasun ChakrabortyKevin HiomNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Prasun Chakraborty
Kevin Hiom
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
description DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.
format article
author Prasun Chakraborty
Kevin Hiom
author_facet Prasun Chakraborty
Kevin Hiom
author_sort Prasun Chakraborty
title DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
title_short DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
title_full DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
title_fullStr DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
title_full_unstemmed DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
title_sort dhx9-dependent recruitment of brca1 to rna promotes dna end resection in homologous recombination
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/71d188e599e54f27b436ad5a2b697995
work_keys_str_mv AT prasunchakraborty dhx9dependentrecruitmentofbrca1tornapromotesdnaendresectioninhomologousrecombination
AT kevinhiom dhx9dependentrecruitmentofbrca1tornapromotesdnaendresectioninhomologousrecombination
_version_ 1718387271020838912