DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.
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Nature Portfolio
2021
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oai:doaj.org-article:71d188e599e54f27b436ad5a2b6979952021-12-02T15:23:19ZDHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination10.1038/s41467-021-24341-z2041-1723https://doaj.org/article/71d188e599e54f27b436ad5a2b6979952021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24341-zhttps://doaj.org/toc/2041-1723DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection.Prasun ChakrabortyKevin HiomNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
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Science Q Prasun Chakraborty Kevin Hiom DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination |
description |
DHX9 is an RNA helicase involved in the processing of pre-mRNA during transcription. Here the authors reveal a role for DHX9 in the initiation of homologues recombination during the early steps of end-resection. |
format |
article |
author |
Prasun Chakraborty Kevin Hiom |
author_facet |
Prasun Chakraborty Kevin Hiom |
author_sort |
Prasun Chakraborty |
title |
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination |
title_short |
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination |
title_full |
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination |
title_fullStr |
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination |
title_full_unstemmed |
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination |
title_sort |
dhx9-dependent recruitment of brca1 to rna promotes dna end resection in homologous recombination |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/71d188e599e54f27b436ad5a2b697995 |
work_keys_str_mv |
AT prasunchakraborty dhx9dependentrecruitmentofbrca1tornapromotesdnaendresectioninhomologousrecombination AT kevinhiom dhx9dependentrecruitmentofbrca1tornapromotesdnaendresectioninhomologousrecombination |
_version_ |
1718387271020838912 |