Kaposi Sarcoma Herpesvirus Induces HO-1 during <italic toggle="yes">De Novo</italic> Infection of Endothelial Cells via Viral miRNA-Dependent and -Independent Mechanisms

ABSTRACT Kaposi sarcoma (KS) herpesvirus (KSHV) infection of endothelial cells (EC) is associated with strong induction of heme oxygenase-1 (HO-1), a stress-inducible host gene that encodes the rate-limiting enzyme responsible for heme catabolism. KS is an angioproliferative tumor characterized by t...

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Auteurs principaux: Sara Botto, Jennifer E. Totonchy, Jean K. Gustin, Ashlee V. Moses
Format: article
Langue:EN
Publié: American Society for Microbiology 2015
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Accès en ligne:https://doaj.org/article/71d738a75a394381a51ab4e24220fb7d
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