Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

The isolation and propagation of oligodendroglial cells from postnatal animals can be impractical for functional genetic studies. This study highlights the potential of a new approach to rapidly generate oligodendrocytes and their progenitors from mouse embryonic and induced pluripotent stem cells,...

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Auteurs principaux:	Angela M. Lager, Olivia G. Corradin, Jared M. Cregg, Matthew S. Elitt, H. Elizabeth Shick, Benjamin L. L. Clayton, Kevin C. Allan, Hannah E. Olsen, Mayur Madhavan, Paul J. Tesar
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/71dbdedc40fa404b962276780906a9a8
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spelling	oai:doaj.org-article:71dbdedc40fa404b962276780906a9a82021-12-02T17:33:06ZRapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells10.1038/s41467-018-06102-72041-1723https://doaj.org/article/71dbdedc40fa404b962276780906a9a82018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06102-7https://doaj.org/toc/2041-1723The isolation and propagation of oligodendroglial cells from postnatal animals can be impractical for functional genetic studies. This study highlights the potential of a new approach to rapidly generate oligodendrocytes and their progenitors from mouse embryonic and induced pluripotent stem cells, independent of mouse strain or mutational status.Angela M. LagerOlivia G. CorradinJared M. CreggMatthew S. ElittH. Elizabeth ShickBenjamin L. L. ClaytonKevin C. AllanHannah E. OlsenMayur MadhavanPaul J. TesarNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Angela M. Lager Olivia G. Corradin Jared M. Cregg Matthew S. Elitt H. Elizabeth Shick Benjamin L. L. Clayton Kevin C. Allan Hannah E. Olsen Mayur Madhavan Paul J. Tesar Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
description	The isolation and propagation of oligodendroglial cells from postnatal animals can be impractical for functional genetic studies. This study highlights the potential of a new approach to rapidly generate oligodendrocytes and their progenitors from mouse embryonic and induced pluripotent stem cells, independent of mouse strain or mutational status.
format	article
author	Angela M. Lager Olivia G. Corradin Jared M. Cregg Matthew S. Elitt H. Elizabeth Shick Benjamin L. L. Clayton Kevin C. Allan Hannah E. Olsen Mayur Madhavan Paul J. Tesar
author_facet	Angela M. Lager Olivia G. Corradin Jared M. Cregg Matthew S. Elitt H. Elizabeth Shick Benjamin L. L. Clayton Kevin C. Allan Hannah E. Olsen Mayur Madhavan Paul J. Tesar
author_sort	Angela M. Lager
title	Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
title_short	Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
title_full	Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
title_fullStr	Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
title_full_unstemmed	Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
title_sort	rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/71dbdedc40fa404b962276780906a9a8
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Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells

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