Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation

Abstract Instrumental learning is mediated by goal-directed and habit systems in the brain. While rodent studies implicate distinct prefrontal/striatal regions in goal-directed and habit learning, neural systems underpinning these two processes in humans remain poorly understood. Here, using a valid...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hamdi Eryilmaz, Anais Rodriguez-Thompson, Alexandra S. Tanner, Madeline Giegold, Franklin C. Huntington, Joshua L. Roffman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/71dc0d3d21984fa9af0537440553fb27
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:71dc0d3d21984fa9af0537440553fb27
record_format	dspace
spelling	oai:doaj.org-article:71dc0d3d21984fa9af0537440553fb272021-12-02T16:07:05ZNeural determinants of human goal-directed vs. habitual action control and their relation to trait motivation10.1038/s41598-017-06284-y2045-2322https://doaj.org/article/71dc0d3d21984fa9af0537440553fb272017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06284-yhttps://doaj.org/toc/2045-2322Abstract Instrumental learning is mediated by goal-directed and habit systems in the brain. While rodent studies implicate distinct prefrontal/striatal regions in goal-directed and habit learning, neural systems underpinning these two processes in humans remain poorly understood. Here, using a validated discrimination learning task that distinguishes goal-directed learning from habit learning in 72 subjects in fMRI, we investigated the corticostriatal correlates of goal-directed learning and tested whether brain activation during learning is associated with trait motivation and behavioral performance in the post-learning test phase. Participants showed enhanced activation in medial prefrontal and posterior cingulate cortices during goal-directed action selection in the training phase, whereas habitual action selection activated bilateral insula, bilateral dorsal caudate and left precentral gyrus. In addition, early phase of learning was associated with increased activation in the frontoparietal control network and dorsal striatum, whereas default mode regions depicted increased activation in the late phase. Finally, avoidance motivation scores measured by Behavioral Inhibition/Activation System (BIS/BAS) correlated with accuracy during goal-directed learning and showed a nominally significant correlation with activation in dorsomedial prefrontal cortex during goal-directed acquisition of stimuli. These findings reveal the temporal dynamics of instrumental behavior and suggest that avoidance motivation predicts performance and brain activity during goal-directed learning.Hamdi EryilmazAnais Rodriguez-ThompsonAlexandra S. TannerMadeline GiegoldFranklin C. HuntingtonJoshua L. RoffmanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hamdi Eryilmaz Anais Rodriguez-Thompson Alexandra S. Tanner Madeline Giegold Franklin C. Huntington Joshua L. Roffman Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
description	Abstract Instrumental learning is mediated by goal-directed and habit systems in the brain. While rodent studies implicate distinct prefrontal/striatal regions in goal-directed and habit learning, neural systems underpinning these two processes in humans remain poorly understood. Here, using a validated discrimination learning task that distinguishes goal-directed learning from habit learning in 72 subjects in fMRI, we investigated the corticostriatal correlates of goal-directed learning and tested whether brain activation during learning is associated with trait motivation and behavioral performance in the post-learning test phase. Participants showed enhanced activation in medial prefrontal and posterior cingulate cortices during goal-directed action selection in the training phase, whereas habitual action selection activated bilateral insula, bilateral dorsal caudate and left precentral gyrus. In addition, early phase of learning was associated with increased activation in the frontoparietal control network and dorsal striatum, whereas default mode regions depicted increased activation in the late phase. Finally, avoidance motivation scores measured by Behavioral Inhibition/Activation System (BIS/BAS) correlated with accuracy during goal-directed learning and showed a nominally significant correlation with activation in dorsomedial prefrontal cortex during goal-directed acquisition of stimuli. These findings reveal the temporal dynamics of instrumental behavior and suggest that avoidance motivation predicts performance and brain activity during goal-directed learning.
format	article
author	Hamdi Eryilmaz Anais Rodriguez-Thompson Alexandra S. Tanner Madeline Giegold Franklin C. Huntington Joshua L. Roffman
author_facet	Hamdi Eryilmaz Anais Rodriguez-Thompson Alexandra S. Tanner Madeline Giegold Franklin C. Huntington Joshua L. Roffman
author_sort	Hamdi Eryilmaz
title	Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
title_short	Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
title_full	Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
title_fullStr	Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
title_full_unstemmed	Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
title_sort	neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/71dc0d3d21984fa9af0537440553fb27
work_keys_str_mv	AT hamdieryilmaz neuraldeterminantsofhumangoaldirectedvshabitualactioncontrolandtheirrelationtotraitmotivation AT anaisrodriguezthompson neuraldeterminantsofhumangoaldirectedvshabitualactioncontrolandtheirrelationtotraitmotivation AT alexandrastanner neuraldeterminantsofhumangoaldirectedvshabitualactioncontrolandtheirrelationtotraitmotivation AT madelinegiegold neuraldeterminantsofhumangoaldirectedvshabitualactioncontrolandtheirrelationtotraitmotivation AT franklinchuntington neuraldeterminantsofhumangoaldirectedvshabitualactioncontrolandtheirrelationtotraitmotivation AT joshualroffman neuraldeterminantsofhumangoaldirectedvshabitualactioncontrolandtheirrelationtotraitmotivation
_version_	1718384722807095296

Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation

Ejemplares similares