Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma.
Asthma is a common allergic lung disease frequently affecting individuals with a prior history of eczema/atopic dermatitis (AD); however, the mechanism underlying the progression from AD to asthma (the so-called "atopic march") is unclear. Here we show that, like humans with AD, mice with...
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Autores principales: | Shadmehr Demehri, Mitsuru Morimoto, Michael J Holtzman, Raphael Kopan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/71df762ecb14474ca89534d3d02d348d |
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