Gambogic amide inhibits angiogenesis by suppressing VEGF/VEGFR2 in endothelial cells in a TrkA-independent manner
Context Gambogic amide (GA-amide) is a non-peptide molecule that has high affinity for tropomyosin receptor kinase A (TrkA) and possesses robust neurotrophic activity, but its effect on angiogenesis is unclear. Objective The study investigates the antiangiogenic effect of GA-amide on endothelial cel...
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Main Authors: | Tongtong Sui, Bojun Qiu, Jiaorong Qu, Yuxin Wang, Kunnian Ran, Wei Han, Xiaozhong Peng |
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Format: | article |
Language: | EN |
Published: |
Taylor & Francis Group
2021
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Subjects: | |
Online Access: | https://doaj.org/article/71e716cae65a4e7eb8c52117ebb95918 |
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