The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins

The mitochondrial protein import machinery is crucial for eukaryotes but little is known about its evolutionary origin. Here, the authors characterize the translocase of the inner membrane (TIM) in trypanosomes, showing that it contains two rhomboid-like proteins essential for protein import.

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Autores principales: Anke Harsman, Silke Oeljeklaus, Christoph Wenger, Jonathan L. Huot, Bettina Warscheid, André Schneider
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/71e9d79a4a73445c930fdcca41bf6ec0
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spelling oai:doaj.org-article:71e9d79a4a73445c930fdcca41bf6ec02021-12-02T17:31:32ZThe non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins10.1038/ncomms137072041-1723https://doaj.org/article/71e9d79a4a73445c930fdcca41bf6ec02016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13707https://doaj.org/toc/2041-1723The mitochondrial protein import machinery is crucial for eukaryotes but little is known about its evolutionary origin. Here, the authors characterize the translocase of the inner membrane (TIM) in trypanosomes, showing that it contains two rhomboid-like proteins essential for protein import.Anke HarsmanSilke OeljeklausChristoph WengerJonathan L. HuotBettina WarscheidAndré SchneiderNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anke Harsman
Silke Oeljeklaus
Christoph Wenger
Jonathan L. Huot
Bettina Warscheid
André Schneider
The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
description The mitochondrial protein import machinery is crucial for eukaryotes but little is known about its evolutionary origin. Here, the authors characterize the translocase of the inner membrane (TIM) in trypanosomes, showing that it contains two rhomboid-like proteins essential for protein import.
format article
author Anke Harsman
Silke Oeljeklaus
Christoph Wenger
Jonathan L. Huot
Bettina Warscheid
André Schneider
author_facet Anke Harsman
Silke Oeljeklaus
Christoph Wenger
Jonathan L. Huot
Bettina Warscheid
André Schneider
author_sort Anke Harsman
title The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
title_short The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
title_full The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
title_fullStr The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
title_full_unstemmed The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
title_sort non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/71e9d79a4a73445c930fdcca41bf6ec0
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