Mouse primary microglia respond differently to LPS and poly(I:C) in vitro

Abstract Microglia, CNS resident innate immune cells, respond strongly to activation of TLR3 and TLR4, which recognize viral dsRNA poly(I:C) and bacterial endotoxin LPS, respectively. However, few studies have thoroughly and parallelly compared functional phenotypes and downstream mechanisms between...

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Bibliographic Details
Main Authors: Yingbo He, Natalie Taylor, Xiang Yao, Anindya Bhattacharya
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/71eb2cdc93b4460cb1a03ab83fade020
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