Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence

Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women developing preeclampsia-possible link to enhanced senescence

Abstract Senescence in placenta/fetal membranes is a normal phenomenon linked to term parturition. However, excessive senescence which may be induced by telomere attrition, has been associated with preeclampsia (PE). We hypothesized that the telomerase complex in peripheral blood mononuclear cells (...

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Autores principales: T. Lekva, M. C. P. Roland, M. E. Estensen, E. R. Norwitz, T. Tilburgs, T. Henriksen, J. Bollerslev, K. R. Normann, P. Magnus, O. K. Olstad, P. Aukrust, T. Ueland
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/71ebd5ffe5f54d9cbc9e34dbe0b359d1
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