Chromosome segregation occurs by microtubule pushing in oocytes
In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle con...
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Nature Portfolio
2017
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oai:doaj.org-article:71f96c6c7ac34a67b76cccc61cc80a1b2021-12-02T14:40:35ZChromosome segregation occurs by microtubule pushing in oocytes10.1038/s41467-017-01539-82041-1723https://doaj.org/article/71f96c6c7ac34a67b76cccc61cc80a1b2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01539-8https://doaj.org/toc/2041-1723In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle control chromosomal segregation.Kimberley LabandRémi Le BorgneFrances EdwardsMarine StefanuttiJulie C. CanmanJean-Marc VerbavatzJulien DumontNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Kimberley Laband Rémi Le Borgne Frances Edwards Marine Stefanutti Julie C. Canman Jean-Marc Verbavatz Julien Dumont Chromosome segregation occurs by microtubule pushing in oocytes |
description |
In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle control chromosomal segregation. |
format |
article |
author |
Kimberley Laband Rémi Le Borgne Frances Edwards Marine Stefanutti Julie C. Canman Jean-Marc Verbavatz Julien Dumont |
author_facet |
Kimberley Laband Rémi Le Borgne Frances Edwards Marine Stefanutti Julie C. Canman Jean-Marc Verbavatz Julien Dumont |
author_sort |
Kimberley Laband |
title |
Chromosome segregation occurs by microtubule pushing in oocytes |
title_short |
Chromosome segregation occurs by microtubule pushing in oocytes |
title_full |
Chromosome segregation occurs by microtubule pushing in oocytes |
title_fullStr |
Chromosome segregation occurs by microtubule pushing in oocytes |
title_full_unstemmed |
Chromosome segregation occurs by microtubule pushing in oocytes |
title_sort |
chromosome segregation occurs by microtubule pushing in oocytes |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/71f96c6c7ac34a67b76cccc61cc80a1b |
work_keys_str_mv |
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_version_ |
1718390244043128832 |