Chromosome segregation occurs by microtubule pushing in oocytes

In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle con...

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Autores principales: Kimberley Laband, Rémi Le Borgne, Frances Edwards, Marine Stefanutti, Julie C. Canman, Jean-Marc Verbavatz, Julien Dumont
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/71f96c6c7ac34a67b76cccc61cc80a1b
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spelling oai:doaj.org-article:71f96c6c7ac34a67b76cccc61cc80a1b2021-12-02T14:40:35ZChromosome segregation occurs by microtubule pushing in oocytes10.1038/s41467-017-01539-82041-1723https://doaj.org/article/71f96c6c7ac34a67b76cccc61cc80a1b2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01539-8https://doaj.org/toc/2041-1723In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle control chromosomal segregation.Kimberley LabandRémi Le BorgneFrances EdwardsMarine StefanuttiJulie C. CanmanJean-Marc VerbavatzJulien DumontNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kimberley Laband
Rémi Le Borgne
Frances Edwards
Marine Stefanutti
Julie C. Canman
Jean-Marc Verbavatz
Julien Dumont
Chromosome segregation occurs by microtubule pushing in oocytes
description In oocytes of most species atypical spindles assembled in the absence of centrosomes drive chromosome segregation, however the forces driving this process are unclear. Here the authors found that spindle poles are largely dispensable and that inter-chromosomal microtubules of the central spindle control chromosomal segregation.
format article
author Kimberley Laband
Rémi Le Borgne
Frances Edwards
Marine Stefanutti
Julie C. Canman
Jean-Marc Verbavatz
Julien Dumont
author_facet Kimberley Laband
Rémi Le Borgne
Frances Edwards
Marine Stefanutti
Julie C. Canman
Jean-Marc Verbavatz
Julien Dumont
author_sort Kimberley Laband
title Chromosome segregation occurs by microtubule pushing in oocytes
title_short Chromosome segregation occurs by microtubule pushing in oocytes
title_full Chromosome segregation occurs by microtubule pushing in oocytes
title_fullStr Chromosome segregation occurs by microtubule pushing in oocytes
title_full_unstemmed Chromosome segregation occurs by microtubule pushing in oocytes
title_sort chromosome segregation occurs by microtubule pushing in oocytes
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/71f96c6c7ac34a67b76cccc61cc80a1b
work_keys_str_mv AT kimberleylaband chromosomesegregationoccursbymicrotubulepushinginoocytes
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AT marinestefanutti chromosomesegregationoccursbymicrotubulepushinginoocytes
AT julieccanman chromosomesegregationoccursbymicrotubulepushinginoocytes
AT jeanmarcverbavatz chromosomesegregationoccursbymicrotubulepushinginoocytes
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