Fractional re-distribution among cell motility states during ageing

Phillip and colleagues use dermal fibroblasts from a range of donors to quantify cell motility in ageing cells. They show that the age-dependent decrease in cell motility is not due to the reduced motility of all cells, but results from the fractional redistribution among motility states.

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Bibliographic Details
Main Authors: Jude M. Phillip, Nahuel Zamponi, Madonna P. Phillip, Jena Daya, Shaun McGovern, Wadsworth Williams, Katherine Tschudi, Hasini Jayatilaka, Pei-Hsun Wu, Jeremy Walston, Denis Wirtz
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/71fdc1a8a32e4767a22e8879599c3e9f
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Summary:Phillip and colleagues use dermal fibroblasts from a range of donors to quantify cell motility in ageing cells. They show that the age-dependent decrease in cell motility is not due to the reduced motility of all cells, but results from the fractional redistribution among motility states.