Fractional re-distribution among cell motility states during ageing

Phillip and colleagues use dermal fibroblasts from a range of donors to quantify cell motility in ageing cells. They show that the age-dependent decrease in cell motility is not due to the reduced motility of all cells, but results from the fractional redistribution among motility states.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jude M. Phillip, Nahuel Zamponi, Madonna P. Phillip, Jena Daya, Shaun McGovern, Wadsworth Williams, Katherine Tschudi, Hasini Jayatilaka, Pei-Hsun Wu, Jeremy Walston, Denis Wirtz
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Accès en ligne:https://doaj.org/article/71fdc1a8a32e4767a22e8879599c3e9f
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:Phillip and colleagues use dermal fibroblasts from a range of donors to quantify cell motility in ageing cells. They show that the age-dependent decrease in cell motility is not due to the reduced motility of all cells, but results from the fractional redistribution among motility states.