NY-ESO-1-specific circulating CD4+ T cells in ovarian cancer patients are prevalently T(H)1 type cells undetectable in the CD25+ FOXP3+ Treg compartment.

NY-ESO-1-specific circulating CD4+ T cells in ovarian cancer patients are prevalently T(H)1 type cells undetectable in the CD25+ FOXP3+ Treg compartment.

Spontaneous CD4(+) T-cell responses to the tumor-specific antigen NY-ESO-1 (ESO) are frequently found in patients with epithelial ovarian cancer (EOC). If these responses are of effector or/and Treg type, however, has remained unclear. Here, we have used functional approaches together with recently...

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Autores principales: Nassima Redjimi, Karine Duperrier-Amouriaux, Isabelle Raimbaud, Immanuel Luescher, Danijel Dojcinovic, Jean-Marc Classe, Dominique Berton-Rigaud, Jean-Sébastien Frenel, Emmanuelle Bourbouloux, Danila Valmori, Maha Ayyoub
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/72191bbdfda1414c9260fa0ce840fd80
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https://doaj.org/article/72191bbdfda1414c9260fa0ce840fd80

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