Insight into the direct interaction of Na+ with NhaA and mechanistic implications
Abstract Na+/H+ antiporters comprise a family of membrane proteins evolutionarily conserved in all kingdoms of life that are essential in cellular ion homeostasis. While several human homologues have long been drug targets, NhaA of Escherichia coli has become the paradigm for this class of secondary...
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Main Authors: | Matthias Quick, Manish Dwivedi, Etana Padan |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/721bce5313a84b5289f7dd4b58c7b205 |
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