Anti-metastatic effect of methylprednisolone targeting vascular endothelial cells under surgical stress

Abstract Perioperative systemic inflammation induced by surgical stress elevates the risk of hematogenous cancer metastasis. This study investigated the anti-metastatic effects and mechanisms of methylprednisolone (MP) administration for surgical stress. We examined the effects of MP on the expressi...

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Main Authors: Takaomi Hagi, Yukinori Kurokawa, Noboru Kobayashi, Tsuyoshi Takahashi, Takuro Saito, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Makoto Yamasaki, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/721c71d72d4545deaa88e9e452b89840
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