A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins
ABSTRACT Cell-autonomous immunity relies on the rapid detection of invasive pathogens by host proteins. Guanylate binding proteins (GBPs) have emerged as key mediators of vertebrate immune defense through their ability to recognize a diverse array of intracellular pathogens and pathogen-containing c...
Guardado en:
Autores principales: | Kristin M. Kohler, Miriam Kutsch, Anthony S. Piro, Graham D. Wallace, Jörn Coers, Matthew F. Barber |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/721fbbdb05764fda8e3d02eb4fe03d8b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents <named-content content-type="genus-species">Burkholderia thailandensis</named-content>-Induced Multinucleated Giant Cell Formation
por: Marisa Dilucca, et al.
Publicado: (2021) -
Essential Role of mGBP7 for Survival of <named-content content-type="genus-species">Toxoplasma gondii</named-content> Infection
por: Nora Steffens, et al.
Publicado: (2020) -
Guanylate Binding Proteins Restrict <named-content content-type="genus-species">Leishmania donovani</named-content> Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting
por: Arun Kumar Haldar, et al.
Publicado: (2020) -
Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins
por: Ryan Finethy, et al.
Publicado: (2017) -
<italic toggle="yes">Shigella sonnei</italic> O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation
por: Jayne L. Watson, et al.
Publicado: (2019)