A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins
ABSTRACT Cell-autonomous immunity relies on the rapid detection of invasive pathogens by host proteins. Guanylate binding proteins (GBPs) have emerged as key mediators of vertebrate immune defense through their ability to recognize a diverse array of intracellular pathogens and pathogen-containing c...
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Main Authors: | Kristin M. Kohler, Miriam Kutsch, Anthony S. Piro, Graham D. Wallace, Jörn Coers, Matthew F. Barber |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Online Access: | https://doaj.org/article/721fbbdb05764fda8e3d02eb4fe03d8b |
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