A Rapidly Evolving Polybasic Motif Modulates Bacterial Detection by Guanylate Binding Proteins

ABSTRACT Cell-autonomous immunity relies on the rapid detection of invasive pathogens by host proteins. Guanylate binding proteins (GBPs) have emerged as key mediators of vertebrate immune defense through their ability to recognize a diverse array of intracellular pathogens and pathogen-containing c...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kristin M. Kohler, Miriam Kutsch, Anthony S. Piro, Graham D. Wallace, Jörn Coers, Matthew F. Barber
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
Sujets:
Accès en ligne:https://doaj.org/article/721fbbdb05764fda8e3d02eb4fe03d8b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!