Dysregulation of bile acids increases the risk for preterm birth in pregnant women

Preterm birth (PTB) is the leading cause of perinatal mortality and newborn complications with limited treatment options. Here the authors show that dysregulation of bile acids increases risk for PTB in pregnant women while restoring bile acid homeostasis delays or prevents PTB in the mouse models.

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Autores principales:	Sangmin You, Ai-Min Cui, Syed F. Hashmi, Xinmu Zhang, Christina Nadolny, Yuan Chen, Qiwen Chen, Xin Bush, Zachary Hurd, Winifer Ali, Gang Qin, Ruitang Deng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/722b7169c06244cc8e509e24c665a7d2
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spelling	oai:doaj.org-article:722b7169c06244cc8e509e24c665a7d22021-12-02T14:41:02ZDysregulation of bile acids increases the risk for preterm birth in pregnant women10.1038/s41467-020-15923-42041-1723https://doaj.org/article/722b7169c06244cc8e509e24c665a7d22020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15923-4https://doaj.org/toc/2041-1723Preterm birth (PTB) is the leading cause of perinatal mortality and newborn complications with limited treatment options. Here the authors show that dysregulation of bile acids increases risk for PTB in pregnant women while restoring bile acid homeostasis delays or prevents PTB in the mouse models.Sangmin YouAi-Min CuiSyed F. HashmiXinmu ZhangChristina NadolnyYuan ChenQiwen ChenXin BushZachary HurdWinifer AliGang QinRuitang DengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sangmin You Ai-Min Cui Syed F. Hashmi Xinmu Zhang Christina Nadolny Yuan Chen Qiwen Chen Xin Bush Zachary Hurd Winifer Ali Gang Qin Ruitang Deng Dysregulation of bile acids increases the risk for preterm birth in pregnant women
description	Preterm birth (PTB) is the leading cause of perinatal mortality and newborn complications with limited treatment options. Here the authors show that dysregulation of bile acids increases risk for PTB in pregnant women while restoring bile acid homeostasis delays or prevents PTB in the mouse models.
format	article
author	Sangmin You Ai-Min Cui Syed F. Hashmi Xinmu Zhang Christina Nadolny Yuan Chen Qiwen Chen Xin Bush Zachary Hurd Winifer Ali Gang Qin Ruitang Deng
author_facet	Sangmin You Ai-Min Cui Syed F. Hashmi Xinmu Zhang Christina Nadolny Yuan Chen Qiwen Chen Xin Bush Zachary Hurd Winifer Ali Gang Qin Ruitang Deng
author_sort	Sangmin You
title	Dysregulation of bile acids increases the risk for preterm birth in pregnant women
title_short	Dysregulation of bile acids increases the risk for preterm birth in pregnant women
title_full	Dysregulation of bile acids increases the risk for preterm birth in pregnant women
title_fullStr	Dysregulation of bile acids increases the risk for preterm birth in pregnant women
title_full_unstemmed	Dysregulation of bile acids increases the risk for preterm birth in pregnant women
title_sort	dysregulation of bile acids increases the risk for preterm birth in pregnant women
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/722b7169c06244cc8e509e24c665a7d2
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Dysregulation of bile acids increases the risk for preterm birth in pregnant women

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