Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome.

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Autores principales: Elliot Stieglitz, Tali Mazor, Adam B. Olshen, Huimin Geng, Laura C. Gelston, Jon Akutagawa, Daniel B. Lipka, Christoph Plass, Christian Flotho, Farid F. Chehab, Benjamin S. Braun, Joseph F. Costello, Mignon L. Loh
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/722c1dde424443b9b6f04f8e32625fea
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spelling oai:doaj.org-article:722c1dde424443b9b6f04f8e32625fea2021-12-02T14:42:01ZGenome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia10.1038/s41467-017-02178-92041-1723https://doaj.org/article/722c1dde424443b9b6f04f8e32625fea2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02178-9https://doaj.org/toc/2041-1723Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome.Elliot StieglitzTali MazorAdam B. OlshenHuimin GengLaura C. GelstonJon AkutagawaDaniel B. LipkaChristoph PlassChristian FlothoFarid F. ChehabBenjamin S. BraunJoseph F. CostelloMignon L. LohNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Elliot Stieglitz
Tali Mazor
Adam B. Olshen
Huimin Geng
Laura C. Gelston
Jon Akutagawa
Daniel B. Lipka
Christoph Plass
Christian Flotho
Farid F. Chehab
Benjamin S. Braun
Joseph F. Costello
Mignon L. Loh
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
description Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome.
format article
author Elliot Stieglitz
Tali Mazor
Adam B. Olshen
Huimin Geng
Laura C. Gelston
Jon Akutagawa
Daniel B. Lipka
Christoph Plass
Christian Flotho
Farid F. Chehab
Benjamin S. Braun
Joseph F. Costello
Mignon L. Loh
author_facet Elliot Stieglitz
Tali Mazor
Adam B. Olshen
Huimin Geng
Laura C. Gelston
Jon Akutagawa
Daniel B. Lipka
Christoph Plass
Christian Flotho
Farid F. Chehab
Benjamin S. Braun
Joseph F. Costello
Mignon L. Loh
author_sort Elliot Stieglitz
title Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
title_short Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
title_full Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
title_fullStr Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
title_full_unstemmed Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
title_sort genome-wide dna methylation is predictive of outcome in juvenile myelomonocytic leukemia
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/722c1dde424443b9b6f04f8e32625fea
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