Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia
Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome.
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Nature Portfolio
2017
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oai:doaj.org-article:722c1dde424443b9b6f04f8e32625fea2021-12-02T14:42:01ZGenome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia10.1038/s41467-017-02178-92041-1723https://doaj.org/article/722c1dde424443b9b6f04f8e32625fea2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02178-9https://doaj.org/toc/2041-1723Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome.Elliot StieglitzTali MazorAdam B. OlshenHuimin GengLaura C. GelstonJon AkutagawaDaniel B. LipkaChristoph PlassChristian FlothoFarid F. ChehabBenjamin S. BraunJoseph F. CostelloMignon L. LohNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017) |
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Science Q |
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Science Q Elliot Stieglitz Tali Mazor Adam B. Olshen Huimin Geng Laura C. Gelston Jon Akutagawa Daniel B. Lipka Christoph Plass Christian Flotho Farid F. Chehab Benjamin S. Braun Joseph F. Costello Mignon L. Loh Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia |
description |
Juvenile myelomonocytic leukemia (JMML) is an aggressive disease with limited options for treatment. Here, the authors utilize DNA methylation based subgroups in JMML to predict clinical outcome. |
format |
article |
author |
Elliot Stieglitz Tali Mazor Adam B. Olshen Huimin Geng Laura C. Gelston Jon Akutagawa Daniel B. Lipka Christoph Plass Christian Flotho Farid F. Chehab Benjamin S. Braun Joseph F. Costello Mignon L. Loh |
author_facet |
Elliot Stieglitz Tali Mazor Adam B. Olshen Huimin Geng Laura C. Gelston Jon Akutagawa Daniel B. Lipka Christoph Plass Christian Flotho Farid F. Chehab Benjamin S. Braun Joseph F. Costello Mignon L. Loh |
author_sort |
Elliot Stieglitz |
title |
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia |
title_short |
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia |
title_full |
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia |
title_fullStr |
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia |
title_full_unstemmed |
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia |
title_sort |
genome-wide dna methylation is predictive of outcome in juvenile myelomonocytic leukemia |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/722c1dde424443b9b6f04f8e32625fea |
work_keys_str_mv |
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