Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
Objectives. Previously we have shown that 20 days after the tumor cells injection smaller melanomas have been developed in chemically sympathectomized mice in comparison with animals having intact sympathetic nervous system. However, it is known that chemical sympathectomy reduces the sympathetic ne...
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oai:doaj.org-article:722ff43604d145298e246e212dac071f2021-12-02T16:33:00ZSympathectomized tumor-bearing mice survive longer but develop bigger melanomas1336-032910.1515/enr-2016-0022https://doaj.org/article/722ff43604d145298e246e212dac071f2016-10-01T00:00:00Zhttps://doi.org/10.1515/enr-2016-0022https://doaj.org/toc/1336-0329Objectives. Previously we have shown that 20 days after the tumor cells injection smaller melanomas have been developed in chemically sympathectomized mice in comparison with animals having intact sympathetic nervous system. However, it is known that chemical sympathectomy reduces the sympathetic neurotransmission only temporarily. In the present study, we monitored the survival of the sympathectomized mice with melanoma with an attempt to find out how long the suppressing effect of sympathectomy on the melanoma growth may endure.Horvathova LTillinger APadova AMravec BSciendoarticle6-hydroxydopamineb16-f10 melanoma cellsmelanoma development and growthtumor weightDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 50, Iss 4, Pp 207-214 (2016) |
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DOAJ |
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6-hydroxydopamine b16-f10 melanoma cells melanoma development and growth tumor weight Diseases of the endocrine glands. Clinical endocrinology RC648-665 |
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6-hydroxydopamine b16-f10 melanoma cells melanoma development and growth tumor weight Diseases of the endocrine glands. Clinical endocrinology RC648-665 Horvathova L Tillinger A Padova A Mravec B Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
description |
Objectives. Previously we have shown that 20 days after the tumor cells injection smaller melanomas have been developed in chemically sympathectomized mice in comparison with animals having intact sympathetic nervous system. However, it is known that chemical sympathectomy reduces the sympathetic neurotransmission only temporarily. In the present study, we monitored the survival of the sympathectomized mice with melanoma with an attempt to find out how long the suppressing effect of sympathectomy on the melanoma growth may endure. |
format |
article |
author |
Horvathova L Tillinger A Padova A Mravec B |
author_facet |
Horvathova L Tillinger A Padova A Mravec B |
author_sort |
Horvathova L |
title |
Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
title_short |
Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
title_full |
Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
title_fullStr |
Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
title_full_unstemmed |
Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
title_sort |
sympathectomized tumor-bearing mice survive longer but develop bigger melanomas |
publisher |
Sciendo |
publishDate |
2016 |
url |
https://doaj.org/article/722ff43604d145298e246e212dac071f |
work_keys_str_mv |
AT horvathoval sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas AT tillingera sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas AT padovaa sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas AT mravecb sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas |
_version_ |
1718383760932601856 |