Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas

Objectives. Previously we have shown that 20 days after the tumor cells injection smaller melanomas have been developed in chemically sympathectomized mice in comparison with animals having intact sympathetic nervous system. However, it is known that chemical sympathectomy reduces the sympathetic ne...

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Autores principales: Horvathova L, Tillinger A, Padova A, Mravec B
Formato: article
Lenguaje:EN
Publicado: Sciendo 2016
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Acceso en línea:https://doaj.org/article/722ff43604d145298e246e212dac071f
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spelling oai:doaj.org-article:722ff43604d145298e246e212dac071f2021-12-02T16:33:00ZSympathectomized tumor-bearing mice survive longer but develop bigger melanomas1336-032910.1515/enr-2016-0022https://doaj.org/article/722ff43604d145298e246e212dac071f2016-10-01T00:00:00Zhttps://doi.org/10.1515/enr-2016-0022https://doaj.org/toc/1336-0329Objectives. Previously we have shown that 20 days after the tumor cells injection smaller melanomas have been developed in chemically sympathectomized mice in comparison with animals having intact sympathetic nervous system. However, it is known that chemical sympathectomy reduces the sympathetic neurotransmission only temporarily. In the present study, we monitored the survival of the sympathectomized mice with melanoma with an attempt to find out how long the suppressing effect of sympathectomy on the melanoma growth may endure.Horvathova LTillinger APadova AMravec BSciendoarticle6-hydroxydopamineb16-f10 melanoma cellsmelanoma development and growthtumor weightDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 50, Iss 4, Pp 207-214 (2016)
institution DOAJ
collection DOAJ
language EN
topic 6-hydroxydopamine
b16-f10 melanoma cells
melanoma development and growth
tumor weight
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle 6-hydroxydopamine
b16-f10 melanoma cells
melanoma development and growth
tumor weight
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Horvathova L
Tillinger A
Padova A
Mravec B
Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
description Objectives. Previously we have shown that 20 days after the tumor cells injection smaller melanomas have been developed in chemically sympathectomized mice in comparison with animals having intact sympathetic nervous system. However, it is known that chemical sympathectomy reduces the sympathetic neurotransmission only temporarily. In the present study, we monitored the survival of the sympathectomized mice with melanoma with an attempt to find out how long the suppressing effect of sympathectomy on the melanoma growth may endure.
format article
author Horvathova L
Tillinger A
Padova A
Mravec B
author_facet Horvathova L
Tillinger A
Padova A
Mravec B
author_sort Horvathova L
title Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
title_short Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
title_full Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
title_fullStr Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
title_full_unstemmed Sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
title_sort sympathectomized tumor-bearing mice survive longer but develop bigger melanomas
publisher Sciendo
publishDate 2016
url https://doaj.org/article/722ff43604d145298e246e212dac071f
work_keys_str_mv AT horvathoval sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas
AT tillingera sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas
AT padovaa sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas
AT mravecb sympathectomizedtumorbearingmicesurvivelongerbutdevelopbiggermelanomas
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