IL-17-producing γδ T cells switch migratory patterns between resting and activated states
IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiates γδT17 cell trafficking patterns at homeostasis and i...
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Nature Portfolio
2017
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oai:doaj.org-article:7231ed3e23fa45de85a4ea9d25972b362021-12-02T14:40:24ZIL-17-producing γδ T cells switch migratory patterns between resting and activated states10.1038/ncomms156322041-1723https://doaj.org/article/7231ed3e23fa45de85a4ea9d25972b362017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15632https://doaj.org/toc/2041-1723IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiates γδT17 cell trafficking patterns at homeostasis and in inflammatory scenarios.Duncan R. McKenzieErvin E. KaraCameron R. BastowTimona S. TyllisKevin A. FenixCarly E. GregorJasmine J. WilsonRachelle BabbJames C. PatonAxel KalliesStephen L. NuttAnne BrüstleMatthias MackIain ComerfordShaun R. McCollNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q |
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Science Q Duncan R. McKenzie Ervin E. Kara Cameron R. Bastow Timona S. Tyllis Kevin A. Fenix Carly E. Gregor Jasmine J. Wilson Rachelle Babb James C. Paton Axel Kallies Stephen L. Nutt Anne Brüstle Matthias Mack Iain Comerford Shaun R. McColl IL-17-producing γδ T cells switch migratory patterns between resting and activated states |
description |
IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiates γδT17 cell trafficking patterns at homeostasis and in inflammatory scenarios. |
format |
article |
author |
Duncan R. McKenzie Ervin E. Kara Cameron R. Bastow Timona S. Tyllis Kevin A. Fenix Carly E. Gregor Jasmine J. Wilson Rachelle Babb James C. Paton Axel Kallies Stephen L. Nutt Anne Brüstle Matthias Mack Iain Comerford Shaun R. McColl |
author_facet |
Duncan R. McKenzie Ervin E. Kara Cameron R. Bastow Timona S. Tyllis Kevin A. Fenix Carly E. Gregor Jasmine J. Wilson Rachelle Babb James C. Paton Axel Kallies Stephen L. Nutt Anne Brüstle Matthias Mack Iain Comerford Shaun R. McColl |
author_sort |
Duncan R. McKenzie |
title |
IL-17-producing γδ T cells switch migratory patterns between resting and activated states |
title_short |
IL-17-producing γδ T cells switch migratory patterns between resting and activated states |
title_full |
IL-17-producing γδ T cells switch migratory patterns between resting and activated states |
title_fullStr |
IL-17-producing γδ T cells switch migratory patterns between resting and activated states |
title_full_unstemmed |
IL-17-producing γδ T cells switch migratory patterns between resting and activated states |
title_sort |
il-17-producing γδ t cells switch migratory patterns between resting and activated states |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/7231ed3e23fa45de85a4ea9d25972b36 |
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