IL-17-producing γδ T cells switch migratory patterns between resting and activated states

IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiates γδT17 cell trafficking patterns at homeostasis and i...

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Autores principales: Duncan R. McKenzie, Ervin E. Kara, Cameron R. Bastow, Timona S. Tyllis, Kevin A. Fenix, Carly E. Gregor, Jasmine J. Wilson, Rachelle Babb, James C. Paton, Axel Kallies, Stephen L. Nutt, Anne Brüstle, Matthias Mack, Iain Comerford, Shaun R. McColl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7231ed3e23fa45de85a4ea9d25972b36
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spelling oai:doaj.org-article:7231ed3e23fa45de85a4ea9d25972b362021-12-02T14:40:24ZIL-17-producing γδ T cells switch migratory patterns between resting and activated states10.1038/ncomms156322041-1723https://doaj.org/article/7231ed3e23fa45de85a4ea9d25972b362017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15632https://doaj.org/toc/2041-1723IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiates γδT17 cell trafficking patterns at homeostasis and in inflammatory scenarios.Duncan R. McKenzieErvin E. KaraCameron R. BastowTimona S. TyllisKevin A. FenixCarly E. GregorJasmine J. WilsonRachelle BabbJames C. PatonAxel KalliesStephen L. NuttAnne BrüstleMatthias MackIain ComerfordShaun R. McCollNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Duncan R. McKenzie
Ervin E. Kara
Cameron R. Bastow
Timona S. Tyllis
Kevin A. Fenix
Carly E. Gregor
Jasmine J. Wilson
Rachelle Babb
James C. Paton
Axel Kallies
Stephen L. Nutt
Anne Brüstle
Matthias Mack
Iain Comerford
Shaun R. McColl
IL-17-producing γδ T cells switch migratory patterns between resting and activated states
description IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiates γδT17 cell trafficking patterns at homeostasis and in inflammatory scenarios.
format article
author Duncan R. McKenzie
Ervin E. Kara
Cameron R. Bastow
Timona S. Tyllis
Kevin A. Fenix
Carly E. Gregor
Jasmine J. Wilson
Rachelle Babb
James C. Paton
Axel Kallies
Stephen L. Nutt
Anne Brüstle
Matthias Mack
Iain Comerford
Shaun R. McColl
author_facet Duncan R. McKenzie
Ervin E. Kara
Cameron R. Bastow
Timona S. Tyllis
Kevin A. Fenix
Carly E. Gregor
Jasmine J. Wilson
Rachelle Babb
James C. Paton
Axel Kallies
Stephen L. Nutt
Anne Brüstle
Matthias Mack
Iain Comerford
Shaun R. McColl
author_sort Duncan R. McKenzie
title IL-17-producing γδ T cells switch migratory patterns between resting and activated states
title_short IL-17-producing γδ T cells switch migratory patterns between resting and activated states
title_full IL-17-producing γδ T cells switch migratory patterns between resting and activated states
title_fullStr IL-17-producing γδ T cells switch migratory patterns between resting and activated states
title_full_unstemmed IL-17-producing γδ T cells switch migratory patterns between resting and activated states
title_sort il-17-producing γδ t cells switch migratory patterns between resting and activated states
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/7231ed3e23fa45de85a4ea9d25972b36
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