Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine

Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine

Melanie Kripp, Ralf-Dieter HofheinzOnkologisches Zentrum, III. Medizinische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, GermanyAbstract: Liposomal encapsulated cytarabine (DepoCyte®, Mundipharma GmbH, Limburg/Lahn, Germany) is a slow-relea...

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Autores principales: Melanie Kripp, Ralf-Dieter Hofheinz
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2008
Materias:
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/7235414629a54c10b36467883a4fcbc5
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spelling oai:doaj.org-article:7235414629a54c10b36467883a4fcbc52021-12-02T00:40:16ZTreatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine1176-91141178-2013https://doaj.org/article/7235414629a54c10b36467883a4fcbc52008-09-01T00:00:00Zhttp://www.dovepress.com/treatment-of-lymphomatous-and-leukemic-meningitis-with-liposomal-encap-a2262https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Melanie Kripp, Ralf-Dieter HofheinzOnkologisches Zentrum, III. Medizinische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, GermanyAbstract: Liposomal encapsulated cytarabine (DepoCyte®, Mundipharma GmbH, Limburg/Lahn, Germany) is a slow-release formulation of conventional cytarabine. It is licensed for intrathecal use in patients with lymphomatous and leukemic meningitis. DepoCyte® obtained superior response rates, improved patient quality of life and improved the time to neurological progression in a randomized albeit small clinical trial. In this review we briefly summarize the clinical data and discuss them in light of clinical problems and possible treatment scenarios.Keywords: liposomal cytarabine, leukemic meningitis, lymphomatous meningitis Melanie KrippRalf-Dieter HofheinzDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2008, Iss Issue 4, Pp 397-401 (2008)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Melanie Kripp
Ralf-Dieter Hofheinz
Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
description Melanie Kripp, Ralf-Dieter HofheinzOnkologisches Zentrum, III. Medizinische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, GermanyAbstract: Liposomal encapsulated cytarabine (DepoCyte®, Mundipharma GmbH, Limburg/Lahn, Germany) is a slow-release formulation of conventional cytarabine. It is licensed for intrathecal use in patients with lymphomatous and leukemic meningitis. DepoCyte® obtained superior response rates, improved patient quality of life and improved the time to neurological progression in a randomized albeit small clinical trial. In this review we briefly summarize the clinical data and discuss them in light of clinical problems and possible treatment scenarios.Keywords: liposomal cytarabine, leukemic meningitis, lymphomatous meningitis
format article
author Melanie Kripp
Ralf-Dieter Hofheinz
author_facet Melanie Kripp
Ralf-Dieter Hofheinz
author_sort Melanie Kripp
title Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
title_short Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
title_full Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
title_fullStr Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
title_full_unstemmed Treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
title_sort treatment of lymphomatous and leukemic meningitis with liposomal encapsulated cytarabine
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/7235414629a54c10b36467883a4fcbc5
work_keys_str_mv AT melaniekripp treatmentoflymphomatousandleukemicmeningitiswithliposomalencapsulatedcytarabine
AT ralfdieterhofheinz treatmentoflymphomatousandleukemicmeningitiswithliposomalencapsulatedcytarabine
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