Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update

Stevens-Johnson syndrome (SJS) is a form of toxic epidermal necrolysis (TEN) a rare but life-threatening hypersensitivity reactions that affect the skin and mucous membranes. The most common triggers are drugs, but they can also be triggered by infections. Granulysin has been recently identified as...

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Autores principales:	O. Mogole, N. Schellack, M. H. Motswaledi
Formato:	article
Lenguaje:	EN
Publicado:	AOSIS 2016
Materias:	steven-johnsons syndrome (sjs) toxic epidermal necrolysis (ten) granulysin supportive care hypersensitivity immunomodulating Medicine R
Acceso en línea:	https://doaj.org/article/723d31e4ae984d6589a231eea0bc9728
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spelling	oai:doaj.org-article:723d31e4ae984d6589a231eea0bc97282021-11-24T07:44:19ZStevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update2078-61902078-620410.4102/safp.v58i5.4570https://doaj.org/article/723d31e4ae984d6589a231eea0bc97282016-11-01T00:00:00Zhttps://safpj.co.za/index.php/safpj/article/view/4570https://doaj.org/toc/2078-6190https://doaj.org/toc/2078-6204Stevens-Johnson syndrome (SJS) is a form of toxic epidermal necrolysis (TEN) a rare but life-threatening hypersensitivity reactions that affect the skin and mucous membranes. The most common triggers are drugs, but they can also be triggered by infections. Granulysin has been recently identified as the major molecule responsible for the widespread keratinocyte necrosis. Early identification and removal of causative agent is crucial in preventing progression of condition and reducing patient mortality. Supportive care is often recommended over immunomodulating treatments as it helps improve patient outcome.O. MogoleN. SchellackM. H. MotswalediAOSISarticlesteven-johnsons syndrome (sjs)toxic epidermal necrolysis (ten)granulysinsupportive carehypersensitivityimmunomodulatingMedicineRENSouth African Family Practice, Vol 58, Iss 5, Pp 57-59 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	steven-johnsons syndrome (sjs) toxic epidermal necrolysis (ten) granulysin supportive care hypersensitivity immunomodulating Medicine R
spellingShingle	steven-johnsons syndrome (sjs) toxic epidermal necrolysis (ten) granulysin supportive care hypersensitivity immunomodulating Medicine R O. Mogole N. Schellack M. H. Motswaledi Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
description	Stevens-Johnson syndrome (SJS) is a form of toxic epidermal necrolysis (TEN) a rare but life-threatening hypersensitivity reactions that affect the skin and mucous membranes. The most common triggers are drugs, but they can also be triggered by infections. Granulysin has been recently identified as the major molecule responsible for the widespread keratinocyte necrosis. Early identification and removal of causative agent is crucial in preventing progression of condition and reducing patient mortality. Supportive care is often recommended over immunomodulating treatments as it helps improve patient outcome.
format	article
author	O. Mogole N. Schellack M. H. Motswaledi
author_facet	O. Mogole N. Schellack M. H. Motswaledi
author_sort	O. Mogole
title	Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
title_short	Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
title_full	Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
title_fullStr	Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
title_full_unstemmed	Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update
title_sort	stevens-johnson syndrome (sjs) and toxic epidermal necrolysis (ten): an update
publisher	AOSIS
publishDate	2016
url	https://doaj.org/article/723d31e4ae984d6589a231eea0bc9728
work_keys_str_mv	AT omogole stevensjohnsonsyndromesjsandtoxicepidermalnecrolysistenanupdate AT nschellack stevensjohnsonsyndromesjsandtoxicepidermalnecrolysistenanupdate AT mhmotswaledi stevensjohnsonsyndromesjsandtoxicepidermalnecrolysistenanupdate
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Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN): an update

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